Effect of Utilizing Virtual Reality With Pulmonary Rehabilitation on Depression in COPD Patients

NCT07790627 | Completed DMC

• 1 other identifier: IRB-PGS-2026-03-0095
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this study is to find the effect of utilizing virtual reality with pulmonary rehabilitation on depression in COPD patients. The main question it aims to answer is: Does utilizing virtual reality with pulmonary rehabilitation reduce depression in COPD patients?

Conditions

COPD Patients; Depression in Chronic Obstructive Pulmonary Disease

Outcome Measures

Primary Outcomes (1)

• depression

  The primary outcome was the change in the depression score from baseline to post intervention. Depression was assessed prior to the first session of pulmonary rehabilitation program and reassessed after the completion of the twelfth session by Beck's Depression Inventory-II (BDI-II). BDI-II is a 21 item questionnaire which measures the severity of depression in adults and adolescents. It is structured on a 4 point rating scale for each question from 0 indicating no presence of any symptoms and 3 indicating that symptoms strongly present. Total scores from 0 to 13 indicate no or minimal depression, scores from 14 to 19 indicate mild depression, while scores from 20 to 28 indicate moderate depression, and scores from 29 to 63 indicate severe depression (Beck, A. T., 1996; NaviauxLab., 2020; Rahat et al., 2012). Patients with depressive symptoms score with a cut off of 14 as mild score indicating clinically significant were included in the study.

  6 weeks

Secondary Outcomes (4)

• anxiety

  6 weeks

• functional capacity

  6 weeks

• sequential attendance of pulmonary rehabilitation sessions

  12 sessions

• compliance with medication

  12 sessions

Study Arms (2)

Experimental group

EXPERIMENTAL

Device: virtual reality with pulmonary rehabilitation

controlled group

OTHER

controlled group received pulmonary rehabilitation

Other: controlled group received pulmonary rehabilitation without utilizing virtual reality

Interventions

virtual reality with pulmonary rehabilitation DEVICE

Virtual reality was utilized with pulmonary rehabilitation in COPD patients in the expiremental group

Experimental group

controlled group received pulmonary rehabilitation without utilizing virtual reality OTHER

controlled group received pulmonary rehabilitation without utilizing virtual reality

controlled group

Eligibility Criteria

• Age: 45 Years - 85 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients with a confirmed diagnosis of COPD, aged between 45 and 85 years and presenting with depression according to the score of BDI-II with a cut off of 14 at the baseline assessment.

You may not qualify if:

• Absence of depression based on BDI-II score, presence of serious psychiatric disorders at the time of evaluation or documented in the medical records, initiation of psychiatric treatment during the study period, contraindications for virtual reality exposure such as (significant vision issues, significant hearing issues, severe motion sickness, seizure disorders) and the patient's refusal to participate.

Sponsors & Collaborators

• Imam Abdulrahman Bin Faisal University: lead

Study Sites (1)

Qatif Central Hospital

Dammam, Eastern Province, Saudi Arabia

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 7, 2026
• First Posted: August 27, 2026
• Study Start: February 2, 2026
• Primary Completion: May 21, 2026
• Study Completion: May 21, 2026
• Last Updated: August 27, 2026

Record last verified: 2026-08

Data Sharing

• IPD Sharing: Will not share

Locations

SA (1)