Assessment of Risk Factors for Incisional Hernia Following Major Abdominal Surgery

NCT07790172 | Recruiting

• 1 other identifier: Soh-Med-26-8-17MS
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to assess the independent patient-related and surgery-related risk factors associated with the development of incisional hernia following major abdominal surgeries.

Conditions

Incisional Hernia Occurence

Outcome Measures

Primary Outcomes (1)

• surgical site infection

  Incidence of surgical site infection following major abdominal surgery, as a risk factor for incisional hernia

  within 10 days after surgery

Study Arms (2)

cases

Patients who developed incisional hernia following major abdominal surgery performed during the preceding two years.

Other: cases

controls

Patients who underwent major abdominal surgery during the same period but did not develop incisional hernia.

Other: controls

Interventions

cases OTHER

Patients who developed incisional hernia following major abdominal surgery performed during the preceding two years.

cases

controls OTHER

Patients who underwent major abdominal surgery during the same period but did not develop incisional hernia.

controls

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The study will include eligible patients identified from the hospital medical records of the Department of General Surgery, Surgical Oncology and Laparoscopic Surgery at Sohag University Hospital. Patients will be classified into two groups: * Cases: Patients who developed incisional hernia following major abdominal surgery performed during the preceding two years. * Controls: Patients who underwent major abdominal surgery during the same period but did not develop incisional hernia. Controls will be randomly selected from the same source population as the cases using a computer-generated random-number sequence, at a 1:1 ratio to ensure comparability between the two groups.

You may qualify if:

• Patients aged 18 years or older.
• patients who underwent major abdominal surgery including both elective and emergency surgeries.
• Patients with complete medical records and operative data.
• Patients willing to participate in the study.

You may not qualify if:

• Patients younger than 18 years.
• Patients with recurrent incisional hernia.
• Patients with incomplete medical records or missing data on key study variables.
• Patients who refused to participate in the study.

Sponsors & Collaborators

• Sohag University: lead

Study Sites (1)

Sohag University Hospital

Sohag, Egypt

RECRUITING

Related Publications (3)

• Rios-Diaz AJ, Morris MP, Christopher AN, Patel V, Broach RB, Heniford BT, Hsu JY, Fischer JP. National epidemiologic trends (2008-2018) in the United States for the incidence and expenditures associated with incisional hernia in relation to abdominal surgery. Hernia. 2022 Oct;26(5):1355-1368. doi: 10.1007/s10029-022-02644-4. Epub 2022 Aug 25.

  PMID: 36006563 BACKGROUND

• Itatsu K, Yokoyama Y, Sugawara G, Kubota H, Tojima Y, Kurumiya Y, Kono H, Yamamoto H, Ando M, Nagino M. Incidence of and risk factors for incisional hernia after abdominal surgery. Br J Surg. 2014 Oct;101(11):1439-47. doi: 10.1002/bjs.9600. Epub 2014 Aug 14.

  PMID: 25123379 BACKGROUND

• Gignoux B, Bayon Y, Martin D, Phan R, Augusto V, Darnis B, Sarazin M. Incidence and risk factors for incisional hernia and recurrence: Retrospective analysis of the French national database. Colorectal Dis. 2021 Jun;23(6):1515-1523. doi: 10.1111/codi.15581. Epub 2021 Apr 5.

  PMID: 33570808 BACKGROUND

Central Study Contacts

Shaza M Diaa, Demonstrator

CONTACT

+201119093616; shazadiaa7@gmail.com

Samir A Abdel Mageed, Professor

CONTACT

+201006837073

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Demonstrator, Department of Family Medicine, Faculty of Medicine, Sohag University

Study Record Dates

• First Submitted: August 24, 2026
• First Posted: August 27, 2026
• Study Start: August 1, 2026
• Primary Completion (Estimated): February 1, 2027
• Study Completion (Estimated): February 1, 2027
• Last Updated: August 27, 2026

Record last verified: 2026-08

Locations

EG (1)