Activating Voice Journaling for Mental Health With Voice Biomarkers

NCT07789808 | Completed

• 1 other identifier: 1
• Study Type: observational
• Target: 50,000
• Locations: 1 country
• Sites: 1

Brief Summary

This retrospective observational study evaluated the relationship between voice characteristics and self-reported mental health symptoms using longitudinal data collected through the Kintsugi Voice Journaling app. Participants provided voice recordings and completed the Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorder-7 (GAD-7) over time. The study analyzed previously collected data to evaluate whether voice biomarkers could be associated with symptoms of depression and anxiety.

Conditions

Depression / Major Depressive Disorder; Anxiety

Keywords

voice biomarkers; speech biomarkers; digital phenotyping; mental health; depression; anxiety; PHQ-9; GAD-7; voice journaling

Outcome Measures

Primary Outcomes (1)

• Association Between Voice Biomarkers and Depressive Symptom Severity (PHQ-9)

  Association between voice biomarkers and depressive symptom severity as measured by the Patient Health Questionnaire-9 (PHQ-9). The PHQ-9 is a 9-item self-report measure of depressive symptom severity; each item is scored 0-3 and total scores range from 0 to 27, with higher scores indicating greater (worse) depressive symptom severity.

  Through study completion, up to 24 months

Secondary Outcomes (1)

• Association Between Voice Biomarkers and Anxiety Symptom Severity (GAD-7)

  Through study completion, up to 24 months

Study Arms (1)

Kintsugi Voice Journaling App Users

Individuals who used the Kintsugi Voice Journaling app and contributed voice recordings along with self-reported PHQ-9 and/or GAD-7 assessments during routine use of the application. No intervention was assigned as part of this study; all data were collected previously during routine app use and analyzed retrospectively.

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population consisted of users of the Kintsugi Voice Journaling app, a mobile application available globally, who had previously contributed voice recordings and self-reported mental health questionnaire data during routine use of the application. Participants were not recruited at a physical study site; all data were contributed remotely through the app. No participants meeting the inclusion criteria were excluded from the analysis.

You may qualify if:

• Use of the Kintsugi Voice Journaling app during the observation period
• Previously collected voice recording data available from use of the app
• At least one completed PHQ-9 and/or GAD-7 assessment during the observation period

Sponsors & Collaborators

• Kintsugi Mindful Wellness, Inc.: lead

Study Sites (1)

Kintsugi Mindful Wellness, Inc.

Berkeley, California, 94707, United States

Location

MeSH Terms

Conditions

Depression; Depressive Disorder, Major; Anxiety Disorders; Psychological Well-Being

Condition Hierarchy (Ancestors)

Behavioral Symptoms; Behavior; Depressive Disorder; Mood Disorders; Mental Disorders; Personal Satisfaction

Study Officials

• Grace Chang

  Kintsugi Mindful Wellness, Inc.

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 12, 2026
• First Posted: August 27, 2026
• Study Start: October 1, 2019
• Primary Completion: October 1, 2021
• Study Completion: October 1, 2021
• Last Updated: August 27, 2026

Record last verified: 2026-08

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)