NCT07787741|Recruiting
Cervical Epidural Block in Chronic Neck Pain
CNP-TREAT
Comparison of Cervical Epidural Block Alone Versus Combined Treatment Modalities in Chronic Neck Pain
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CNP-TREAT
Comparison of Cervical Epidural Block Alone Versus Combined Treatment Modalities in Chronic Neck Pain
Sponsor study identifier
interventional
60
1 country
1
Study Start
July 1, 2026
Actual (reported)Primary Completion
October 1, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
October 1, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Chronic neck pain can negatively affect daily activities, work ability, and quality of life. Cervical epidural block is commonly used to reduce pain and inflammation, while exercise and physical therapy aim to improve muscle strength, endurance, movement control, and physical function. However, there is limited evidence comparing cervical epidural block alone with its combined use with exercise or physical therapy. This study aims to compare the effects of three treatment approaches in patients with chronic neck pain associated with cervical disc pathology or degenerative changes. Participants will receive cervical epidural block alone, cervical epidural block combined with cervical stabilization exercises, or cervical epidural block combined with physical therapy. Pain intensity, neck-related disability, and quality of life will be evaluated before treatment and at 1, 3, and 6 months after treatment using the Numeric Rating Scale, Neck Disability Index, and 12-Item Short Form Health Survey. The study will determine whether adding exercise or physical therapy to cervical epidural block provides additional clinical and functional benefits.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
October 1, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
July 1, 2026
Actual (reported)August 22, 2026
Actual (reported)August 26, 2026
Actual (reported)October 1, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
October 1, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Change in Pain Intensity Assessed by the Numeric Rating Scale
Pain intensity will be assessed using the Numeric Rating Scale (NRS). Participants rate their pain on an 11-point scale ranging from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain. Lower scores indicate lower pain intensity. Changes from baseline will be compared among the three treatment groups.
Baseline and 1, 3, and 6 months after treatment
Change in Neck-Related Disability Assessed by the Neck Disability Index
Baseline and 1, 3, and 6 months after treatment
Change in Health-Related Quality of Life Assessed by the 12-Item Short Form Health Survey
Baseline and 1, 3, and 6 months after treatment
Participants in this arm receive cervical epidural steroid injection alone.
Participants in this arm receive cervical epidural steroid injection combined with a cervical stabilization exercise program.
Participants receive a cervical epidural steroid injection for the treatment of chronic neck pain associated with cervical radiculopathy.
Sakarya Training and Research Hospital
Adapazarı, Sakarya, 54100, Turkey (Türkiye)
KEMAL NAS, MD, Professor
Sakarya University Training and Research Hospital, Department of Algology
RIDVAN IŞIK, MD
Sakarya University Training and Research Hospital, Department of Algology
First Submitted
August 22, 2026
First Posted
August 26, 2026
Study Start
July 1, 2026
Actual (reported)Participants in this arm receive cervical epidural steroid injection combined with a physical therapy program.
Participants perform a cervical stabilization exercise program in addition to cervical epidural steroid injection.
Participants receive a physical therapy program in addition to cervical epidural steroid injection.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
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Primary Completion
October 1, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
October 1, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Last Updated
September 8, 2026
Record last verified: 2026-08
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Source: ClinicalTrials.gov.
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