NCT07787455

Brief Summary

the aim from the study is goal directed fluid therapy in carniotomy operations guided by ppv versus cvp

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jan 2026

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 11, 2026

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 11, 2026

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2026

Completed
22 days until next milestone

First Submitted

Initial submission to the registry

August 23, 2026

Completed
3 days until next milestone

First Posted

Study publicly available on registry

August 26, 2026

Completed
Last Updated

August 26, 2026

Status Verified

August 1, 2026

Enrollment Period

4 months

First QC Date

August 23, 2026

Last Update Submit

August 23, 2026

Conditions

VOLUME OF FLUID

Outcome Measures

Primary Outcomes (1)

  • TOTAL VOLUME OF FLUIDS

    COMPARE INRAOPRETIVE CRYSTELLOIDS VOLUMES BETWEEN CVP GUDIED AND PPV GUDIED GROUP IN CRANIOTOMY OPERATIONS

    INTRAOPRETIVE TIME SNICE INDUCTION TILL END OF OPERATION

Study Arms (2)

CVP GROUP

SHOULD BE BETWWEN 8-10 CMH2O

PPV GROUP

KEEP PPV LESS THAN 13%

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

PT WAS RANDOMLY ALLOACTED TO 2 GROUPS GROUP A : CVP BETWEEN 8-10 CMH2O GROUP B : PPV LESS THAN 13 %

You may qualify if:

  • ASA I,II AGE 18-65

You may not qualify if:

  • CHRONIC CARDIC ARRHYTHMIA FLASE HIGH CVP ALTERED MYOCARDIAL FUNCTION PERIPHRAL VASCULAR DISEASE SEVER RESPRITORY DISEASE PEREGANACY PATIENT REFUSAL EXCESSIVE BLOOD LOSS OPERATIONS

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ain Shams University

Cairo, Egypt

Location

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
6 Months
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 23, 2026

First Posted

August 26, 2026

Study Start

January 11, 2026

Primary Completion

May 11, 2026

Study Completion

August 1, 2026

Last Updated

August 26, 2026

Record last verified: 2026-08

Locations

EG(1)