Postoperative Pain Management for Hip Surgeries: UltrasoundGuided Suprainguinal Fascia Iliaca Compartment Block Versus Suprainguinal Fascia Iliaca Compartment Block in Combination With Sciatic Nerve Block

NCT07787442 | Completed Phase 1

• 1 other identifier: FMASU MS 763/2025
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the Study is to compare the analgesic efficacy and clinical outcomes of suprainguinal fascia iliaca block (SIFIB) alone versus SIFIB combined with sciatic nerve block (SNB) in patients undergoing hip surgery.

Conditions

Postoperative Pain

Outcome Measures

Primary Outcomes (1)

• Time for first rescue analgesia

  Time to first request for rescue analgesia: Defined as the time interval from the end of procedure until the patient's first complaint of pain with a Numerical Rating Scale (NRS) score ≥ 4 and requests pain relief

  Numerical Pain Score in PACU, 6 hrs, 12 hrs, 24 hrs and 48 hrs postoperative

Secondary Outcomes (1)

• Motor Block Assessment

  The Modified Bromage Scale at 2 , 6 , 12 and 24 hours postoperatively

Study Arms (2)

Ultrasound Guided Suprainguinal Fascia Iliaca Compartment Block

ACTIVE COMPARATOR

Drug: Bupivacaine injection

Ultrasound Guided Suprainguinal Fascia Iliaca Compartment Block in combination with Sciatic Nerve Bl

ACTIVE COMPARATOR

Drug: Bupivacaine injection

Interventions

Bupivacaine injection DRUG

Bupivacaine injection

Ultrasound Guided Suprainguinal Fascia Iliaca Compartment Block; Ultrasound Guided Suprainguinal Fascia Iliaca Compartment Block in combination with Sciatic Nerve Bl

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age: 18 - 70 years old.
• Sex: Both sexes.
• American Society of Anesthesiologists (ASA) physical status I , II, III, IV.
• Hip surgeries e.g.: Total hip arthroplasty, Hemi-arthroplasty, Fracture neck of femur under spinal anesthesia

You may not qualify if:

• Refusal to participate.
• Known allergy to local anesthetics.
• Coagulopathy or anticoagulant therapy contraindicating regional anesthesia.
• Pre-existing neurological deficits in the lower limbs.
• Infection at the injection site.
• Severe cognitive impairment or inability to assess pain (e.g., advanced dementia).
• Failed spinal anesthesia.
• Body mass index (BMI) \>40 kg / m²

Sponsors & Collaborators

• Ain Shams University: lead

Study Sites (1)

Ain Shams University

Cairo, Abbassia, 00202, Egypt

Location

MeSH Terms

Conditions

Pain, Postoperative

Interventions

Bupivacaine

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Intervention Hierarchy (Ancestors)

Anilides; Amides; Organic Chemicals; Aniline Compounds; Amines

Study Design

• Study Type: interventional
• Phase: phase 1
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 23, 2026
• First Posted: August 26, 2026
• Study Start: November 2, 2025
• Primary Completion: May 2, 2026
• Study Completion: June 2, 2026
• Last Updated: August 26, 2026

Record last verified: 2026-08

Locations

EG (1)