Clinical, Hematological and Pathological Profile of Pancytopenia

NCT07785726 | Not Yet Recruiting

• 1 other identifier: Pancytopenia
• Study Type: observational
• Target: 140
• Locations: 0 countries
• Sites: N/A

Brief Summary

Describe clinical characteristic, peripheral blood parameters and bone marrow examination in pancytopenia patients and Analyze etiology of pancytopenia and study the outcomes regarding duration of hospital stay.

Conditions

Pancytopenia

Keywords

pancytopenia

Outcome Measures

Primary Outcomes (1)

• Proportion of underlying etiologies of pancytopenia

  Percentage of study participants diagnosed with each etiology of pancytopenia based on clinical, hematological, and pathological evaluation

  At the time of patient enrollment and initial diagnostic workup

Secondary Outcomes (2)

• Frequency of clinical features and hematological parameters in pancytopenia patients

  At baseline

• Distribution of bone marrow pathological findings

  At baseline

Study Arms (1)

Pancytopenia Cases

Patients presenting with clinical and laboratory features of pancytopenia who are admitted to or evaluated at Assiut University Hospitals. This group includes individuals undergoing routine clinical, hematological, and pathological assessments to identify the underlying causes of their condition.

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population consists of patients of different age groups and both sexes who present with clinical manifestations and laboratory findings suggestive of pancytopenia, attending the inpatient departments or outpatient clinics at Assiut University Hospitals.

You may qualify if:

• Adults aged ≥ 18 years suffering from pancytopenia. Pancytopenia defined as a hematologic condition characterized by a decrease in all three peripheral blood cell lines. It is characterized by a hemoglobin value of less than 12 g/dL in women and 13 g/dL in men, platelets of less than 150,000 per mcL, and leukocytes of less than 4000 per ml (or absolute neutrophil count of less than 1800 per ml), (Chiravuri, Shalini, and Orlando De Jesus. "Pancytopenia.". StatPearls Publishing, 2023).

Sponsors & Collaborators

• Assiut University: lead

MeSH Terms

Conditions

Pancytopenia

Condition Hierarchy (Ancestors)

Cytopenia; Hematologic Diseases; Hemic and Lymphatic Diseases

Study Officials

• Mai Mostafa mohamed kamal, Prof

  Assiut University

  STUDY CHAIR

Central Study Contacts

rana mohamed zain, MBBCh

CONTACT

+201026597669; ranahafez119@gmail.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: resident physician

Study Record Dates

• First Submitted: August 20, 2026
• First Posted: August 25, 2026
• Study Start: August 1, 2026
• Primary Completion: August 1, 2026
• Study Completion (Estimated): October 1, 2028
• Last Updated: August 25, 2026

Record last verified: 2026-08

Data Sharing

• IPD Sharing: Will not share