NCT07785531

Brief Summary

Clinical Characteristics, Etiology, Short-Term Outcomes, and Performance of Contemporary Risk Stratification Scores in Acute Heart Failure Patients Presenting to Assiut University Heart Hospital.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
350

participants targeted

Target at P75+ for all trials

Timeline
24mo left

Started Aug 2026

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress4%
Aug 2026Sep 2028

Study Start

First participant enrolled

August 1, 2026

Completed
7 days until next milestone

First Submitted

Initial submission to the registry

August 8, 2026

Completed
17 days until next milestone

First Posted

Study publicly available on registry

August 25, 2026

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2028

Expected
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2028

Last Updated

August 25, 2026

Status Verified

July 1, 2026

Enrollment Period

2 years

First QC Date

August 8, 2026

Last Update Submit

August 23, 2026

Conditions

Keywords

Risk stratification scores

Outcome Measures

Primary Outcomes (1)

  • Clinical Characteristics, Etiology, Short-Term Outcomes, and Performance of Contemporary Risk Stratification Scores in Acute Heart Failure Patients Presenting to Assiut University Heart Hospital.

    To externally validate the HEARTRISK6 score and evaluate its predictive performance for short-term adverse outcomes in patients with acute heart failure. History of moderate/severe valvular heart disease\_Yes. 1 Heart rate \>100 to ≤120 bpm. 2 \>120 bpm. 3 Non-invasive ventilation (NIV)BiPAP/NIV within first hour 2 Creatinine \>150 to ≤300 µmol/L 2 \>300 µmol/L. 3 Troponin \>3-5 × upper reference limit (URL) 1 \>5 × URL. 2 Failed reassessment / 3-minute walk test ifFailed1 comp0 High score means worse

    Follow up patients for 30 days

Interventions

EchoDIAGNOSTIC_TEST

Echo for clinical assessment

EcgDIAGNOSTIC_TEST

Twelve leads ECG to detect any ischemic changes

CreatinineDIAGNOSTIC_TEST

To detect renal function test

TroponinDIAGNOSTIC_TEST

Ischemic changes

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Acute heart failure patients presenting to Emergency Department and Cardiology Department, Assiut University Hospitals, Egypt.

You may qualify if:

  • Age more than 18yrs
  • Clinical diagnosis of acute heart failure according to current ESC guideline criteria.

You may not qualify if:

  • Age below than 18
  • Refusal to participate.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

AssiutU

Asyut, Egypt

Location

Related Publications (1)

  • McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Bohm M, Burri H, Butler J, Celutkiene J, Chioncel O, Cleland JGF, Coats AJS, Crespo-Leiro MG, Farmakis D, Gilard M, Heymans S, Hoes AW, Jaarsma T, Jankowska EA, Lainscak M, Lam CSP, Lyon AR, McMurray JJV, Mebazaa A, Mindham R, Muneretto C, Francesco Piepoli M, Price S, Rosano GMC, Ruschitzka F, Kathrine Skibelund A; ESC Scientific Document Group. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J. 2021 Sep 21;42(36):3599-3726. doi: 10.1093/eurheartj/ehab368. No abstract available.

MeSH Terms

Interventions

CavesElectrocardiography

Intervention Hierarchy (Ancestors)

Geological PhenomenaPhysical PhenomenaEnvironmentEcological and Environmental PhenomenaBiological PhenomenaEnvironment and Public HealthHeart Function TestsDiagnostic Techniques, CardiovascularDiagnostic Techniques and ProceduresDiagnosisElectrodiagnosis

Central Study Contacts

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Resident

Study Record Dates

First Submitted

August 8, 2026

First Posted

August 25, 2026

Study Start

August 1, 2026

Primary Completion (Estimated)

August 1, 2028

Study Completion (Estimated)

September 1, 2028

Last Updated

August 25, 2026

Record last verified: 2026-07

Data Sharing

IPD Sharing
Will share

Locations