True Muscle Transplantation Surgery Versus Augmented Semi Hang Back Recession in Large Angle Exotropia: Evaluation of Efficacy and Lateral Gaze Incomitance

NCT07784842 | Recruiting

• 1 other identifier: MiniaU-Oph- 2026-EXOT-01
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

This a randomized clinical trial comparing True muscle transplantation surgery versus Augmented Semi hang back recession for treatment of large angle exotropia

Conditions

Large Angle Exotropia

Keywords

exotropia,strabismus,muscle transplantation,augmented recession

Outcome Measures

Primary Outcomes (1)

• Surgical success rate at 6 months

  Proportion of patients with ocular alignment within 10 prism diopters of orthotropia measured by prism and alternate cover test

  6 months post-surgery

Study Arms (2)

True Muscle Transplantation Surgery

EXPERIMENTAL

Patients in this group will undergo True Muscle Transplantation Surgery For treatment of large angle exotropia

Procedure: True Muscle Transplantation Surgery

Augmented Semi hang back Recession

EXPERIMENTAL

Patients in this group will undergo Augmented Semi hang back Recession for treatment of large angle exotropia

Procedure: Augmented Semi hang back Recession

Interventions

True Muscle Transplantation Surgery PROCEDURE

true Muscle Transplantation surgery for treatment of large angle Exotropia

True Muscle Transplantation Surgery

Augmented Semi hang back Recession PROCEDURE

Augmented Semi hang back Recession for treatment of large angle Exotropia

Augmented Semi hang back Recession

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients with large angle exotropia more than 50 prism diopters.
• No previous squint surgery.

You may not qualify if:

• Patients with severe ocular surface diseases as ocular cicatricial pemphigoid and severe dry eye.
• Severe systemic illness that prevents general anesthesia

Sponsors & Collaborators

• Hassnaa Mohamed Abdelhameed Ahmed: lead

Study Sites (1)

Minya University Hospital - Ophthalmology Department

Minya, Minya Governorate, 61111, Egypt

RECRUITING

MeSH Terms

Conditions

Exotropia

Condition Hierarchy (Ancestors)

Strabismus; Ocular Motility Disorders; Cranial Nerve Diseases; Nervous System Diseases; Eye Diseases

Central Study Contacts

Hassnaa Mohamed Abdelhameed, Assistant lecturer

CONTACT

+201158861290; hasnaa.abdelhamid@mu.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Assistant Lecturer of Ophthalmology, Minia University

Model Details: Patients will be randomly assigned to 1 of 2 surgical intervention arms

Study Record Dates

• First Submitted: August 20, 2026
• First Posted: August 25, 2026
• Study Start: March 1, 2026
• Primary Completion (Estimated): October 1, 2026
• Study Completion (Estimated): January 1, 2027
• Last Updated: August 25, 2026

Record last verified: 2026-08

Locations

EG (1)