The Correlation Between Sodium Urate (MSU) Deposition and Coronary Atherosclerosis in Patients With Foot Gout

NCT07784049 | Not Yet Recruiting

• 1 other identifier: QYFYEC2026-30
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

This observational study aims to evaluate the association between sodium urate deposition volume and coronary atherosclerotic plaques in patients with foot gout using dual-energy CT (DECT) and coronary CTA. This study will explore imaging-based evidence for the progression and risk prediction of adverse cardiovascular events in patients with gout.

Conditions

Gout; Coronary Atheroma

Outcome Measures

Primary Outcomes (1)

• Volume of sodium urate deposition and coronary artery plaque volume

  Measurement of sodium urate deposition volume and coronary artery plaque volume in patients with foot gout.

  baseline

Interventions

DECT;CCTA DIAGNOSTIC_TEST

Perform DECT and CCTA examinations on the patient

Eligibility Criteria

• Age: 18 Years - 90 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with podagra who have high-risk factors for cardiovascular disease

You may qualify if:

• Aged ≥18 years, male or female
• Clinically diagnosed with podagra
• Having high-risk factors for cardiovascular disease
• Complete clinical data available
• Patients and their family members are informed, consent and have signed the informed consent form

You may not qualify if:

• Women who are preparing for pregnancy, pregnant or breastfeeding
• Male and female subjects of reproductive age who are unable to take effective contraceptive measures
• Patients who cannot or are unable to undergo CTA scans
• Patients with severe heart diseases such as severe heart failure, severe heart valve disease and cardiomyopathy
• Severe hemodynamic instability
• Any other reason making subjects unsuitable to participate in the study, including subjects who are unable or unwilling to comply with the requirements of the study protocol

Sponsors & Collaborators

• The Affiliated Hospital of Qingdao University: lead

Study Sites (1)

The Affiliated Hospital of Qingdao University

Qingdao, Shandong, 266003, China

Location

MeSH Terms

Conditions

Gout; Coronary Artery Disease

Condition Hierarchy (Ancestors)

Arthritis; Joint Diseases; Musculoskeletal Diseases; Crystal Arthropathies; Rheumatic Diseases; Purine-Pyrimidine Metabolism, Inborn Errors; Metabolism, Inborn Errors; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Metabolic Diseases; Nutritional and Metabolic Diseases; Coronary Disease; Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Arteriosclerosis; Arterial Occlusive Diseases; Vascular Diseases

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 18, 2026
• First Posted: August 25, 2026
• Study Start: August 20, 2026
• Primary Completion (Estimated): December 1, 2028
• Study Completion (Estimated): December 1, 2028
• Last Updated: August 25, 2026

Record last verified: 2026-08

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)