NCT07773857

Brief Summary

The aim of this study is to investigate the effects of exercises applied using the Proprioceptive Neuromuscular Facilitation (PNF) technique on pain, joint range of motion, muscle strength, and posture in individuals with Upper Crossed Syndrome, and to compare these effects with patient education. Individuals diagnosed with Upper Crossed Syndrome will be included in the study and allocated into two groups: a PNF-based exercise combined with patient education group and a patient education-only group. In the PNF group, Stabilizing Reversals for scapular anterior elevation-posterior depression and Replication techniques for posterior depression will be applied. In the patient education group, education including postural awareness and exercise will be provided. Assessments will be conducted at two time points, before and after the intervention. Pain level, joint range of motion, muscle strength and endurance, and postural parameters will be analyzed. This study is expected to provide evidence regarding the clinical effectiveness of PNF approaches targeting scapular control in individuals with Upper Crossed Syndrome and to contribute to the management of postural disorders in the field of physiotherapy and rehabilitation.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
38

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Mar 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 5, 2026

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 15, 2026

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

July 15, 2026

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

August 14, 2026

Completed
5 days until next milestone

First Posted

Study publicly available on registry

August 19, 2026

Completed
Last Updated

August 31, 2026

Status Verified

January 1, 2026

Enrollment Period

3 months

First QC Date

August 14, 2026

Last Update Submit

August 26, 2026

Conditions

Keywords

Upper Cross SyndromeProprioseptive Neuromuscular FacilitatitonPNFPatient EducationPosture

Outcome Measures

Primary Outcomes (1)

  • Posture Assesment

    Posture will be assessed using the Posture Screen Mobile (PSM) application (Backbone Software, Inc., USA), a valid and reliable mobile application designed for postural analysis. Participants will be positioned in a static standing posture on a flat surface, with their feet parallel, wearing appropriate clothing that allows visualization of the upper body and lower extremities. Photographs will be taken from the anterior, posterior, and lateral views using a mobile device placed at a standardized distance. During the assessment, the application will automatically identify anatomical reference points (e.g., ears, shoulders, pelvis). Based on these reference points, postural deviations will be calculated and reported by the software. Anterior and posterior postural deviations in the frontal plane and lateral postural deviations in the sagittal plane will be recorded for each participant.

    Baseline and up to 8 weeks

Secondary Outcomes (6)

  • Muscle Strength Assessment

    Baseline and up to 8 weeks

  • Pain Assessment

    Baseline and up to 8 weeks

  • Muscle Endurance

    Baseline and up to 8 weeks

  • Muscle Length Tests

    Baseline and up to 8 weeks

  • Range of Motion Assessment

    Baseline and up to 8 weeks

  • +1 more secondary outcomes

Study Arms (2)

Patient Education Group

ACTIVE COMPARATOR

Participants in the patient education group will receive a single face-to-face patient education session at the beginning of the study.

Behavioral: Patient Education

PNF Group

EXPERIMENTAL

In the PNF group, in addition to patient education, Stabilizing Reversals and Replication techniques with scapular patterns will be performed.

Behavioral: Patient EducationBehavioral: PNF

Interventions

Participants in the patient education group will receive a single face-to-face patient education session at the beginning of the study. This education will include information on postural awareness, correct sitting posture, and maintaining proper posture during activities of daily living. In addition, participants will be provided with a prepared educational brochure and will be asked to perform the two postural exercises included in the brochure three days per week for a total duration of four weeks. Participants will be encouraged to integrate the postural principles taught during the education into their daily lives.

PNF GroupPatient Education Group
PNFBEHAVIORAL

In the PNF, trunk correction in the sitting position, approximation, and the application of Stabilizing Reversals in the direction of scapular posterior depression-anterior elevation and Replication techniques toward scapular posterior depression in the side-lying position will be performed. These interventions are planned to be applied three days per week, with a total intervention duration of four weeks.

PNF Group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 18 years or older
  • Clinically diagnosed with Upper Crossed Syndrome and referred by a specialist physician (e.g., Physical Medicine and Rehabilitation, Orthopedics)
  • Upper Crossed Syndrome diagnosis confirmed at baseline based on postural characteristics (e.g., forward head posture, rounded shoulders, thoracic kyphosis etc.)
  • Willingness to participate in the study and provision of written informed consent

You may not qualify if:

  • History of spinal surgery or spinal fracture
  • Presence of structural spinal deformities (e.g., structural kyphosis or scoliosis)
  • Presence of neuromuscular diseases affecting the spine or upper quadrant
  • Presence of congenital or acquired severe structural spinal anomalies
  • Any medical condition that contraindicates participation in exercise programs
  • History of severe psychiatric disorders
  • History of chronic pain in the cervical or lumbopelvic regions
  • History of postural control disorders
  • Any condition expected to prevent regular participation or adherence during the study period.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Istanbul Atlas University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation

Istanbul, Istanbul, 34408, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Oculocerebral hypopigmentation syndrome type PreusKyphosis

Interventions

Patient Education as Topic

Condition Hierarchy (Ancestors)

Spinal CurvaturesSpinal DiseasesBone DiseasesMusculoskeletal Diseases

Intervention Hierarchy (Ancestors)

Health EducationPreventive Health ServicesHealth ServicesHealth Care Facilities Workforce and Services

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 14, 2026

First Posted

August 19, 2026

Study Start

March 5, 2026

Primary Completion

June 15, 2026

Study Completion

July 15, 2026

Last Updated

August 31, 2026

Record last verified: 2026-01

Locations