Kinesio Taping After Platelet-Rich Plasma Treatment in Individuals With Knee Osteoarthritis

NCT07773324 | Completed

• 2 other identifiers: 2024-1296125S162
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

This randomized controlled study evaluated whether kinesio taping provided additional benefits compared with sham taping in women with knee osteoarthritis who had received platelet-rich plasma (PRP) treatment as part of routine clinical care. Sixty women aged 50 to 65 years with Kellgren-Lawrence grade 1 to 3 knee osteoarthritis were randomly assigned in a 1:1 ratio to either kinesio taping or sham taping. Taping was applied once weekly for 6 weeks. Participants were assessed before taping and at weeks 3, 6, and 12. Outcomes included pain, function, physical performance, knee extensor strength, knee range of motion, and quality of life. The study aimed to determine whether kinesio taping after PRP treatment was more effective than sham taping in improving pain, function, physical performance, knee extensor strength, knee range of motion and quality of life.

Conditions

Osteoarthritis (OA) of the Knee

Keywords

Kinesio Taping; Platelet-Rich Plasma; Sham Taping; Knee Pain; Physical Function

Outcome Measures

Primary Outcomes (2)

• Knee Pain Intensity

  Knee pain was assessed using an 11-point Numerical Rating Scale ranging from 0 (no pain) to 10 (worst imaginable pain). Higher scores indicate greater pain intensity.

  Baseline and Weeks 3, 6, and 12

• Function ((Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC))

  Knee pain, stiffness, and physical function were assessed using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). The pain, stiffness, and physical function subscale scores range from 0 to 20, 0 to 8, and 0 to 68, respectively. The total score ranges from 0 to 96. Higher scores indicate worse pain, stiffness, and functional limitation.

  Baseline and Weeks 3, 6, and 12

Secondary Outcomes (7)

• 30-Second Chair Stand Test

  Baseline and Weeks 3, 6, and 12

• 40-Meter Fast-Paced Walk Test

  Baseline and Weeks 3, 6, and 12

• 9-Step Stair Test

  Baseline and Weeks 3, 6, and 12

• Knee Extensor Strength

  Baseline and Weeks 3, 6, and 12

• Knee Flexion Range of Motion

  Baseline and Weeks 3, 6, and 12

Study Arms (2)

Kinesio Taping

EXPERIMENTAL

Other: Kinesio Taping

Sham Taping

SHAM COMPARATOR

Other: Sham Taping

Interventions

Kinesio Taping OTHER

Therapeutic kinesio taping was applied once weekly for 6 weeks. A Y-cut tape was applied over the quadriceps muscle with 20% to 25% tension. Two web-cut tapes were applied around the knee with 10% to 15% tension. Each application remained in place for 5 days.

Kinesio Taping

Sham Taping OTHER

Sham taping was applied once weekly for 6 weeks. Two strips of tape were placed transversely 10 cm and 20 cm above the superior border of the patella without tape tension or a specific kinesio taping technique. Each application remained in place for 5 days.

Sham Taping

Eligibility Criteria

• Age: 50 Years - 65 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Female participants aged 50 to 65 years
• Diagnosis of unilateral or bilateral knee osteoarthritis according to the American College of Rheumatology criteria
• Kellgren-Lawrence radiographic grade 1 to 3 knee osteoarthritis
• Received three platelet-rich plasma injections at 3-week intervals as part of routine clinical care
• Ability to walk without an assistive device
• Body mass index below 35 kg/m²
• Willingness to participate and provision of written informed consent

You may not qualify if:

• Knee surgery within the previous 6 months
• Intra-articular injection other than platelet-rich plasma within the previous 3 months
• Systemic inflammatory joint disease, including rheumatoid arthritis, ankylosing spondylitis, or gout
• Known allergy or adverse skin reaction to kinesio tape
• Skin condition preventing tape application, including skin sensitivity or an open wound
• Neuromuscular disease causing lower-extremity muscle weakness
• Perceptual or coordination impairment

Sponsors & Collaborators

• Agri Ibrahim Cecen University: lead

Study Sites (1)

Kafkas University Health Research and Application Hospital

Kars, 36100, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Osteoarthritis

Condition Hierarchy (Ancestors)

Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Kübra Ayşe Daşdemir

Study Record Dates

• First Submitted: August 14, 2026
• First Posted: August 19, 2026
• Study Start: May 16, 2025
• Primary Completion: May 16, 2026
• Study Completion: May 16, 2026
• Last Updated: August 19, 2026

Record last verified: 2026-08

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)