Comparison of Two Mechanical Rotation Chairs With Diagnostics of Benign Paroxysmal Positional Vertigo.

NCT07772973 | Enrolling By Invitation

• 1 other identifier: 16-0302-144
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to investigate whether the diagnosis of benign paroxysmal positional vertigo (BPPV) is equally good with two different mechanical rotation chairs (MRCs) (TRV rotary chair and the Rotundum rotary chair). In the study, two different diagnostic criteria will be used (the international Bárány criteria and the American Academy of Otolaryngology-Head and Neck surgery (AAO-HNS) criteria) with both MRCs. Patients with BPPV experience brief attacks of positional vertigo. Typically, this vertigo is provoked by changes in head position relative to gravity, e.g. laying down or turning to the side from the supine position. Previous studies on the use of MRCs have shown that MRCs offer very precise and accurate BPPV diagnostics. With MRCs it is possible to determine 1) laterality (left/right), 2) specific location (specific semicircular canal), and 3) BPPV subtype (canalolithiasis/cupulolithiasis). Treatment-wise, these MRCs have also shown to be very efficient with treatment success rates being above ninety percent. The two MRCs used in this study do not offer the exact same features (e.g. design, portability, fixed positions, and the possibility of adding kinetic energy). To the knowledge of the authors, no studies exist on direct comparison of separate MRCs. The Rotundum rotary chair, which is also the newest of the two MRCs included, has so far not been included in many studies. However, the hypothesis of the current study is that the Rotundum rotary chair and the TRV rotation chair are equally good in terms of BPPV diagnostics.

Conditions

Benign Paroxysmal Positional Vertigo (BPPV)

Keywords

Benign Paroxysmal Positional Vertigo; BPPV; Mechanical Rotation Chair; Rotundum rotary chair; TRV chair; Vertigo

Outcome Measures

Primary Outcomes (2)

• Difference in the ability to diagnose BPPV

  Statistically significant difference in the ability to induce nystagmus and/or vertigo between the TRV chair and Rotundum chair.

  40 minutes

• Agreement on the diagnosis of BPPV in individual semicircular canals and subtype of BPPV

  Statistically significant difference in the ability to induce nystagmus and/or vertigo between the TRV chair and Rotundum chair for each individual semicircular canal and for subtype of BPPV i.e. canalolithiasis or cupulolithiasis.

  40 minutes

Study Arms (4)

TRV chair - Bárány Criteria

A group of participants with suspected BPPV who undergo a diagnostic procedure for BPPV in the TRV chair. The diagnosis, laterality, semicircular canal localization, and subtypes in this group are determined according to the diagnostic criteria published by the Bárány Society.

Device: TRV® (Interacoustics©, Middelfart, Denmark), mechanical rotational chair

Rotundum chair - Bárány Criteria

A group of participants with suspected BPPV who undergo a diagnostic procedure for BPPV in the Rotundum chair. The diagnosis, laterality, semicircular canal localization, and subtypes in this group are determined according to the diagnostic criteria published by the Bárány Society.

Device: Rotundum® (balcare GmbH©, Küsnacht, Switzerland), mechanical rotational chair.

TRV chair - AAO-HNS Criteria

A group of participants with suspected BPPV who undergo a diagnostic procedure for BPPV in the TRV chair. The diagnosis, laterality, semicircular canal localization, and subtypes in this group are determined according to the diagnostic AAO-HNS criteria.

Device: TRV® (Interacoustics©, Middelfart, Denmark), mechanical rotational chair

Rotundum chair - AAO-HNS Criteria

A group of participants with suspected BPPV who undergo a diagnostic procedure for BPPV in the Rotundum chair. The diagnosis, laterality, semicircular canal localization, and subtypes in this group are determined according to the diagnostic AAO-HNS criteria.

Device: Rotundum® (balcare GmbH©, Küsnacht, Switzerland), mechanical rotational chair.

Interventions

TRV® (Interacoustics©, Middelfart, Denmark), mechanical rotational chair DEVICE

Diagnostic positioning maneuvers performed using the TRV® MRC to evaluate the presence, affected semicircular canal, and subtype of Benign Paroxysmal Positional Vertigo.

TRV chair - AAO-HNS Criteria; TRV chair - Bárány Criteria

Rotundum® (balcare GmbH©, Küsnacht, Switzerland), mechanical rotational chair. DEVICE

Diagnostic positioning maneuvers performed using the Rotundum® MRC to evaluate the presence, affected semicircular canal, and subtype of Benign Paroxysmal Positional Vertigo.

Rotundum chair - AAO-HNS Criteria; Rotundum chair - Bárány Criteria

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Subjects are referred by their general practitioner or from a private ENT on the basis of a typical BPPV case history and/or clinical findings suggesting the presence of BPPV to examination in a rotation chair at the investigational site.

You may qualify if:

• ≥ 18 years of age
• Typical BPPV history

You may not qualify if:

• Unable to comply with full diagnostic procedure in TRV and Rotundum rotary chair
• Intake of 1st generation antihistamines within the last 7 days
• Intake of benzodiazepines within the last 7 days
• Known cerebral aneurysm
• Recent cerebral hemorrhagia
• Weight \> 150 kg

Sponsors & Collaborators

• Aalborg University Hospital: lead

Study Sites (1)

Department of Otorhinolaryngology, Head & Neck Surgery and Audiology

Aalborg, North Jutland, 9000, Denmark

Location

Related Publications (5)

• Krzywdzinska S, Rozbicki P, Usowski J, Jurkiewicz D. The use and effectiveness of the TRV Chair - a literature review. Otolaryngol Pol. 2023 Dec 31;77(6):31-36. doi: 10.5604/01.3001.0054.0942.

  PMID: 38706261 BACKGROUND

• Pedersen MF, Eriksen HH, Kjaersgaard JB, Abrahamsen ER, Hougaard DD. Treatment of Benign Paroxysmal Positional Vertigo with the TRV Reposition Chair. J Int Adv Otol. 2020 Aug;16(2):176-182. doi: 10.5152/iao.2020.6320.

  PMID: 32784154 BACKGROUND

• Abdulovski S, Klokker M. Repositioning Chairs in the Diagnosis and Treatment of Benign Paroxysmal Positional Vertigo - A Systematic Review. J Int Adv Otol. 2021 Jul;17(4):353-360. doi: 10.5152/iao.2021.9434.

  PMID: 34309558 BACKGROUND

• Hougaard DD, Duch K, Bech MW. Treatment of posterior Benign Paroxysmal Positional Vertigo is efficient and safe with a new Mechanical Rotational Chair. Front Neurol. 2023 Aug 17;14:1239959. doi: 10.3389/fneur.2023.1239959. eCollection 2023.

  PMID: 37662040 BACKGROUND

• Hougaard DD, Valsted SH, Bruun NH, Bech MW, Talebnasab MH. Seven years of experience with treatment of benign paroxysmal positional vertigo with a mechanical rotational chair. Front Neurol. 2022 Aug 25;13:981216. doi: 10.3389/fneur.2022.981216. eCollection 2022.

  PMID: 36090886 BACKGROUND

MeSH Terms

Conditions

Benign Paroxysmal Positional Vertigo; Vertigo

Condition Hierarchy (Ancestors)

Vestibular Diseases; Labyrinth Diseases; Ear Diseases; Otorhinolaryngologic Diseases; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Lucas Toft, BSc in Medicine

  Aalborg University

  STUDY DIRECTOR

• Jakob M Vandbaek, BSc in Medicine

  Aalborg University

  STUDY DIRECTOR

• Fredrik Lund, BSc in Medicine

  Aalborg University

  STUDY DIRECTOR

• Dan D Hougaard, Medical Doctor

  Department of Otorhinolaryngology, Head & Neck Surgery and Audiology

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Chief Physician and Associate Professor

Study Record Dates

• First Submitted: August 14, 2026
• First Posted: August 19, 2026
• Study Start (Estimated): September 1, 2026
• Primary Completion (Estimated): December 1, 2026
• Study Completion (Estimated): January 1, 2027
• Last Updated: August 19, 2026

Record last verified: 2026-08

Data Sharing

• IPD Sharing: Will not share

Locations

DK (1)