NCT07769190|Completed
Cardiovascular Mortality Prediction in Maintenance Hemodialysis Patients
Development of a Mortality Prediction Model for Patients Receiving Maintenance Hemodialysis
Loading search results
Development of a Mortality Prediction Model for Patients Receiving Maintenance Hemodialysis
Sponsor study identifier
observational
192
1 country
1
Study Start
July 16, 2021
Actual (reported)Primary Completion
April 21, 2022
Actual (reported)Study Completion
April 21, 2022
Actual (reported)This prospective, single-center observational cohort study evaluates cardiovascular mortality risk in adults receiving maintenance hemodialysis. During the first year after enrollment, four scheduled assessments are used to characterize demographic factors, dialysis treatment, medication use, routine laboratory measures, and the proportion of serum phosphate measurements within the protocol-defined target range. Participants are subsequently followed for cardiovascular mortality. The study evaluates factors associated with serum phosphate target achievement and develops a cardiovascular mortality prediction model in the overall cohort, with a prespecified subgroup analysis among participants who undergo parathyroidectomy. No treatment or procedure is assigned by the study investigators.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
April 21, 2022
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
July 16, 2021
Actual (reported)April 21, 2022
Actual (reported)April 21, 2022
Actual (reported)August 12, 2026
Actual (reported)August 17, 2026
Actual (reported)Cardiovascular Mortality
Occurrence and date of death attributed to cardiovascular disease during follow-up, ascertained through study follow-up and available clinical or death records.
Up to 5 years after completion of the 1-year exposure-assessment period
One-Year Serum Phosphate Target Achievement Rate
During the first year after enrollment
Mortality in the Parathyroidectomy Subgroup
Up to 5 years after completion of the 1-year exposure-assessment period
Adults receiving maintenance hemodialysis for at least 3 months at Huashan Hospital are observed without a study-assigned intervention. Demographic, clinical, medication, laboratory, and dialysis-treatment data are recorded during a one-year assessment period, followed by longitudinal ascertainment of cardiovascular mortality. Participants may be classified according to serum phosphate target achievement and parathyroidectomy status for prespecified analyses.
The one-year serum phosphate target achievement rate is calculated as the number of evaluable scheduled serum phosphate measurements within the protocol-defined target range divided by the total number of evaluable scheduled measurements during the first year after enrollment. Four scheduled assessments are planned. Serum phosphate management is determined by routine clinical care and is not assigned by the study investigators.
The study population comprises adults aged 18 to 85 years who have received maintenance hemodialysis for at least 3 months at the Hemodialysis Center of Huashan Hospital, Fudan University. Participants are selected according to the prespecified eligibility criteria and are observed under routine clinical care without a study-assigned treatment.
Huashan hospital, Fudan university
Shanghai, Shanghai Municipality, 200040, China
Jing Chen
Huashan Hospital
192 participants (actual enrollment reported by the registry).
First Submitted
August 12, 2026
First Posted
August 17, 2026
Study Start
July 16, 2021
Actual (reported)Parathyroidectomy received as part of routine clinical care is recorded for prespecified subgroup analysis. The decision to perform parathyroidectomy is made by the treating clinical team and is not assigned by the study investigators.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Contact the study team to confirm eligibility.
Primary Completion
April 21, 2022
Actual (reported)Study Completion
April 21, 2022
Actual (reported)Last Updated
August 17, 2026
Record last verified: 2026-08
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: