A Clinical Trial to Evaluate the Effects of a Powder Supplement in Supporting Lean Muscle Development, Hormone-Related Wellness, Digestive Comfort, Dermatologic Health, and Overall Wellness

NCT07766395 | Recruiting

• 2 other identifiers: 20834legacy-20834
• Study Type: interventional
• Target: 35
• Locations: 1 country
• Sites: 1

Brief Summary

This study will evaluate the effects of Clean Nutra's Shelf Builder Women's Creatine Powder on lean muscle development, hormone-related wellness, digestive comfort, dermatological health, and overall wellness. The study is a single-arm, open-label, virtual trial in which all 35 enrolled participants will use the test product once daily for eight weeks. Participants will complete self-reported questionnaires at Baseline and at the end of Week 4 and Week 8 to assess changes in lean muscle development, muscular endurance, hormone-related wellness, digestive comfort, hair/nail/skin health, and overall wellness.

Conditions

Lean Muscle Development; Muscular Endurance; Hormone-Related Wellness; Digestive Comfort; Dermatologic Health; Overall Wellness

Outcome Measures

Primary Outcomes (8)

• Change in Lean Muscle Development

  Self-reported change in lean muscle development assessed via questionnaire

  Baseline, Week 4, and Week 8

• Change in Muscular Endurance

  Self-reported change in muscular endurance assessed via questionnaire

  Baseline, Week 4, and Week 8

• Change in Digestive Comfort

  Self-reported change in digestive comfort assessed via questionnaire

  Baseline, Week 4, and Week 8

• Change in Hair

  Self-reported change in hair, nail, and skin health assessed via questionnaire

  Baseline, Week 4, and Week 8

• Change in Nail

  Self-reported change in hair, nail, and skin health assessed via questionnaire

  Baseline, Week 4, and Week 8

• Change in Skin Health

  Self-reported change in hair, nail, and skin health assessed via questionnaire

  Baseline, Week 4, and Week 8

• Change in Symptoms of Hormonal Imbalance

  Self-reported change in symptoms of hormonal imbalance assessed via questionnaire

  Baseline, Week 4, and Week 8

• Change in Overall Health and Wellness

  Self-reported change in overall health and wellness assessed via questionnaire

  Baseline, Week 4, and Week 8

Secondary Outcomes (13)

• Perceived Change in Lean Muscle Strength

  Baseline, Week 4, and Week 8

• Perceived Change in Exercise Performance

  Baseline, Week 4, and Week 8

• Perceived Change in Lean Muscle Development

  Baseline, Week 4, and Week 8

• Perceived Change in Hair

  Baseline, Week 4, and Week 8

• Perceived Change in Nail

  Baseline, Week 4, and Week 8

Study Arms (1)

Shelf Builder Women's Creatine Powder

EXPERIMENTAL

Dietary Supplement: Shelf Builder Women's Creatine Powder

Interventions

Shelf Builder Women's Creatine Powder DIETARY_SUPPLEMENT

All participants take one scoop (9 g) of Clean Nutra Shelf Builder Women's Creatine Powder mixed in 8 oz of cold water once daily with the first meal of the day for eight weeks.

Shelf Builder Women's Creatine Powder

Eligibility Criteria

• Age: 21 Years - 45 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Be female.
• Be aged 21-45.
• Engages in structured physical activity ≥3 times per week, with each session lasting at least 30 minutes, (e.g., running, gym/strength training, cycling, team sports, fitness classes).
• Anyone with a menstrual cycle between 24-38 days.
• Anyone who has experienced concerns with at least two of the following, twice per week, over the past four weeks: Hair, skin, and nail health
• Bloating
• Symptoms of hormonal imbalance.
• Anyone with a BMI of 18.5 to 30 kg/m2.
• Anyone who is generally healthy - does not live with any uncontrolled chronic disease.
• If taking medications, other supplements, or herbal remedies targeted at lean muscle development, muscular endurance, digestive comfort, hormonal balance, or dermatological health, has been consistently taking for at least three months prior to starting the study, and is willing to maintain this routine for the study duration.
• Anyone who is willing to maintain their current diet, sleep pattern, and activity levels for the duration of the trial.
• Resides in the United States.

You may not qualify if:

• Anyone with pre-existing chronic conditions that would prevent participants from adhering to the protocol, including oncological and mental health disorders.
• Anyone with a known history of severe digestive disorders like acid reflux, Irritable Bowel Syndrome (IBS), Irritable Bowel Disease (IBD), Crohn's disease, or gastrointestinal tract surgeries.
• Planning on introducing any products or any new forms of prescription medication or supplements that target lean muscle development, muscular endurance, digestive comfort, hormonal balance, or dermatological health for the study duration.
• Anyone who has been diagnosed with kidney disease and/or has previously or is currently taking diuretics or kidney medications.
• Anyone who has previously or is currently taking any hormone therapies.
• Anyone who is currently taking medications or supplements that contain zinc or iron.
• Anyone with any allergies or sensitivities to fish, eggs, or any of the study product ingredients.
• Anyone currently consuming products with creatine.
• Anyone diagnosed with a thyroid-related condition.
• Any women who are pregnant, breastfeeding, or trying to conceive (or who will be at any point during the study period).
• Anyone who has a history of serious illness in the last three months.
• Anyone who has planned surgery during the study period.
• Anyone with a history of substance abuse.
• Anyone who is currently a smoker or has been a smoker in the past 3 months.
• Anyone who has stopped or started using hormonal birth control in the past 2 months.

Sponsors & Collaborators

• Clean Nutraceuticals: lead
• Citruslabs: collaborator

Study Sites (1)

Citruslabs

Las Vegas, Nevada, 89101, United States

RECRUITING

Central Study Contacts

Patrick Renner

CONTACT

hello@citruslabs.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 11, 2026
• First Posted: August 14, 2026
• Study Start (Estimated): September 1, 2026
• Primary Completion (Estimated): November 1, 2026
• Study Completion (Estimated): November 1, 2026
• Last Updated: August 14, 2026

Record last verified: 2026-08

Locations

US (1)