Muscle Function Following Anterior Cruciate Ligament Reconstruction: Impaired Power Output in Physically Active Individuals

NCT07765173 | Recruiting

• 1 other identifier: CHMS26001
• Study Type: interventional
• Target: 110
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to to determine the extent of the association between objective changes in the muscle function of the knee extensors (strength and power) and the function reported by the patient following ACL reconstruction surgery. The main questions it aims to answer is: \- Pre- and post-operative (6 months) changes in maximum knee extensor strength following ACL reconstruction, correlated with the IKDC-SKF score.

Conditions

ACL Surgery

Keywords

assessment; recovery; cruciate ligament; surgery

Outcome Measures

Primary Outcomes (1)

• Correlation of maximum knee extension strength to IKDC-SKF scores

  Relationship (r coefficient) between 0-6 month delta of maximum knee extension strength measurements and International Knee Documentation Commitee-SKF scores (100: no limitation)

  6 month

Secondary Outcomes (9)

• Peri-operatory trajectory of maximal dynamic force

  0, 3 and 6 month

• Peri-operatory trajectory of maximal contraction velocity

  0, 3 and 6 month

• Peri-operatory trajectory of rate of force development

  0, 3 and 6 month

• Peri-operatory trajectory of maximal isometric force

  0, 3 and 6 month

• Peri-operatory trajectory of maximal dynamic force during cycling

  0, 3 and 6 month

Study Arms (1)

evaluated group

EXPERIMENTAL

assessment of knee function before and after cruciate ligament surgery

Other: assessment

Interventions

assessment OTHER

* Assessment of force-velocity and power-velocity relationships in each leg during a cycling task * Assessment of unilateral force-velocity and power-velocity relationships during a knee extension task * Assessment of maximum force and explosive force in isometric (static) conditions of the knee extensors. * Measurement of scores using questionnaires (IKDC-SKF).

evaluated group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients requiring isolated or complex ACL reconstruction (combined with a meniscal injury)
• Patients who are physically active (Tegner score ≥ 4) and wish to resume such activity.
• Patients with no history of surgery on the ipsilateral knee (i.e., native knee).
• Patients able to comply with the study procedures
• Patients who have given their free and informed written consent, having been informed of the purpose of the study, its procedure and its risks.
• Be affiliated to a social security scheme.

You may not qualify if:

• Patient with comprehension difficulties
• Recurrent rupture of the ipsilateral ACL
• Multi-ligament injuries (i.e., injury to the medial collateral ligament, lateral collateral ligament or posterior cruciate ligament)

Sponsors & Collaborators

• Centre Hospitalier Metropole Savoie: lead
• Université Savoie Mont Blanc: collaborator

Study Sites (1)

Médipôle de Savoie

Challes-les-Eaux, 73190, France

RECRUITING

MeSH Terms

Interventions

Restraint, Physical

Intervention Hierarchy (Ancestors)

Behavior Control; Therapeutics; Immobilization; Investigative Techniques

Central Study Contacts

leo blervaque

CONTACT

04.79.96.58.13; leo.blervaque@ch-metropole-savoie.fr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 1, 2026
• First Posted: August 14, 2026
• Study Start: June 8, 2026
• Primary Completion (Estimated): June 8, 2030
• Study Completion (Estimated): June 8, 2030
• Last Updated: August 14, 2026

Record last verified: 2026-08

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)