Early Mobilization and Prolonged ICU Stay in Postoperative Patients

NCT07765017 | Not Yet Recruiting

• 1 other identifier: E-26-954
• Study Type: observational
• Target: 80
• Locations: 0 countries
• Sites: N/A

Brief Summary

This prospective observational cohort study aims to evaluate early mobilization in adult postoperative patients admitted to the intensive care unit (ICU) and to investigate its association with short-term clinical outcomes. Early meaningful mobilization is defined as achieving at least sitting at the edge of the bed (mobilization level ≥4) within the first 24 hours after ICU admission. Patients will be classified according to whether early meaningful mobilization is achieved. The primary objective is to evaluate the association between early meaningful mobilization and prolonged ICU stay. Secondary outcomes include mechanical ventilation requirement and duration, hospital length of stay, need for reintubation, development of delirium, complications occurring during mobilization, and ICU mortality.

Conditions

Early Mobilization; Postoperative Care

Keywords

Early Mobilization; Postoperative Intensive Care; Intensive Care Unit; Prolonged ICU Stay

Outcome Measures

Primary Outcomes (1)

• Prolonged Intensive Care Unit Stay

  Prolonged ICU stay will be evaluated according to the duration of ICU hospitalization and compared between patients who achieve early meaningful mobilization and those who do not. Early meaningful mobilization is defined as achieving a mobilization level of ≥4 within the first 24 hours after ICU admission.

  Through ICU stay, an expected average of 3 days

Secondary Outcomes (5)

• Mechanical Ventilation Requirement

  Through ICU stay, an expected average of 3 days

• Duration of Mechanical Ventilation

  Through ICU stay, an expected average of 3 days

• Hospital Length of Stay

  Through hospitalization, an expected average of 7 days

• Reintubation Requirement

  Through ICU stay, an expected average of 3 days

• ICU Mortality

  Through ICU stay, an expected average of 3 days

Study Arms (2)

Early Meaningful Mobilization

Postoperative ICU patients who achieve a mobilization level of ≥4 within the first 24 hours after ICU admission.

No Early Meaningful Mobilization

Postoperative ICU patients who do not achieve a mobilization level of ≥4 within the first 24 hours after ICU admission.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult postoperative patients admitted to the intensive care unit of Ankara Training and Research Hospital who meet the predefined eligibility criteria will constitute the study population. Participants will be prospectively evaluated for early mobilization during their ICU stay and followed for the clinical outcomes specified in the study protocol.

You may qualify if:

• Age 18 years or older
• Admission to the intensive care unit for postoperative care
• ICU stay of at least 24 hours
• Ability to assess the patient's mobilization level within the first 24 hours following ICU admission
• Provision of informed consent for participation in the study

You may not qualify if:

• Age under 18 years
• Pregnancy
• Death within the first 24 hours after ICU admission
• Clinical conditions contraindicating mobilization, including active massive bleeding, significant hemodynamic instability, unstable fracture, open abdomen, or similar conditions

Sponsors & Collaborators

• Ankara Training and Research Hospital: lead

Study Officials

• Dilek Kuzukıran Kocataş, MD

  Ankara Training and Research Hospital

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Dilek Kuzukıran Kocataş, MD

CONTACT

+905355261001; drdilek06@hotmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: August 7, 2026
• First Posted: August 14, 2026
• Study Start (Estimated): October 15, 2026
• Primary Completion (Estimated): February 15, 2027
• Study Completion (Estimated): May 15, 2027
• Last Updated: August 14, 2026

Record last verified: 2026-08

Data Sharing

• IPD Sharing: Will not share