NCT07764471

Brief Summary

This randomized controlled trial was conducted to evaluate the effectiveness of adding Mulligan Mobilization with Movement (MWM) to conventional physiotherapy in patients with chronic mechanical neck pain. Seventy-six participants aged 18-65 years were randomly assigned to receive either conventional physiotherapy alone or conventional physiotherapy combined with MWM for four weeks. Pain intensity, cervical range of motion, and functional disability were assessed before and after the intervention. The study aimed to compare changes in pain intensity, cervical range of motion, and functional disability between the two treatment groups.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
76

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Feb 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 15, 2026

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 18, 2026

Completed
7 days until next milestone

Study Completion

Last participant's last visit for all outcomes

May 25, 2026

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

August 6, 2026

Completed
8 days until next milestone

First Posted

Study publicly available on registry

August 14, 2026

Completed
Last Updated

August 14, 2026

Status Verified

August 1, 2026

Enrollment Period

3 months

First QC Date

August 6, 2026

Last Update Submit

August 12, 2026

Conditions

Keywords

Chronic neck painMulligan conceptMobilization with MovementCervical range of motionRandomized controlled trial

Outcome Measures

Primary Outcomes (1)

  • Change from baseline in pain intensity measured by Visual Analog Scale (VAS)

    Pain intensity will be measured using the Visual Analog Scale (VAS), a 0-10 cm scale, where 0 indicates no pain and 10 indicates the worst pain. Higher scores indicate greater pain intensity and therefore worse outcomes. Pain intensity will be assessed at baseline and at the end of the 4-week intervention. The change in pain score from baseline to post-intervention will be reported.

    Before treatment (baseline) and 4 weeks (end of treatment)

Secondary Outcomes (2)

  • Change from baseline in cervical range of motion (ROM) measured by goniometer (degrees)

    Before treatment (baseline) and 4 weeks (end of treatment)

  • Change from baseline in neck-related disability measured by the Neck Disability Index (NDI)

    Before treatment (baseline) and 4 weeks (end of treatment)

Study Arms (2)

Control group (A) (n = 32) received a conventional physical therapy program

ACTIVE COMPARATOR
Other: Conventional Physical Therapy Program

The experimental group (B) (n=38) received conventional program, with addition to Mulligan technique

EXPERIMENTAL
Other: Conventional Physical Therapy ProgramOther: Mulligan technique

Interventions

Included of Cervical mobility and strengthening exercises, Transcutaneous Electrical Nerve Stimulation (TENS) and Soft tissue massage

Control group (A) (n = 32) received a conventional physical therapy programThe experimental group (B) (n=38) received conventional program, with addition to Mulligan technique

The Mulligan Concept is a manual therapy approach developed by New Zealand physiotherapist Brian Mulligan in the 1980s. It includes techniques such as Mobilization with Movement (MWM) and the Sustained Natural Apophyseal Glide (SNAG), which have attracted significant attention for their effectiveness in treating neck pain.

Also known as: Mulligan Concept
The experimental group (B) (n=38) received conventional program, with addition to Mulligan technique

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 18-65 years
  • Chronic mechanical neck pain lasting ≥ 3 months
  • NDI score ≥ 10
  • Ability to attend 3 sessions per week

You may not qualify if:

  • Previous cervical spine surgery
  • Cervical radiculopathy or myelopathy
  • Vertebral artery insufficiency
  • Rheumatologic or neurological disorders
  • Ongoing physiotherapy elsewhere

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

PhysioFlex - Physiotherapy and Rehabilitation Center-Nablus

Nablus, Nablus, +970, Palestinian Territories

Location

Study Officials

  • Mosab S Amoudi

    Arab American University (Palestine)

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Assistant Professor of Physical Therapy

Study Record Dates

First Submitted

August 6, 2026

First Posted

August 14, 2026

Study Start

February 15, 2026

Primary Completion

May 18, 2026

Study Completion

May 25, 2026

Last Updated

August 14, 2026

Record last verified: 2026-08

Data Sharing

IPD Sharing
Will not share

Locations