Periodontal Tissue Stability After Surgical Correction of Altered Passive Eruption

NCT07762482 | Recruiting

• 1 other identifier: CAAE: 99545426.9.0000.5419
• Study Type: interventional
• Target: 10
• Locations: 1 country
• Sites: 1

Brief Summary

This prospective, single-group interventional study will evaluate the stability of periodontal tissues after esthetic periodontal surgery for the correction of altered passive eruption in individuals with excessive gingival display. Ten adult participants with excessive gingival display associated with altered passive eruption and involvement of the alveolar bone will be included. Participants will undergo esthetic crown-lengthening surgery consisting of gingivectomy and osseous recontouring. Periodontal clinical measurements, intraoral digital scans, cone-beam computed tomography, standardized photographs, and patient-reported outcomes will be obtained before surgery and during follow-up. Clinical and three-dimensional tissue changes, esthetic perception, satisfaction, and oral health-related quality of life will be evaluated for up to 12 months after treatment.

Conditions

Altered Passive Eruption

Keywords

Gummy Smile; Esthetic Crown Lengthening; Gingivectomy; Osseous Surgery; Periodontal Plastic Surgery; Periodontal Tissue Stability; Intraoral Scanning

Outcome Measures

Primary Outcomes (1)

• Mean Change From Baseline in Clinical Crown Length

  Clinical crown length will be recorded in millimeters. The mean change from baseline will be calculated at each postoperative assessment to evaluate the stability of the surgical outcome over time.

  Baseline, 2 weeks, 3 months, 6 months, and 12 months after surgery

Secondary Outcomes (6)

• Mean Change From Baseline in the Distance Between the Cementoenamel Junction and Alveolar Bone Crest

  Baseline, 3 months, 6 months, and 12 months after surgery

• Mean Change From Baseline in Gingival Thickness

  Baseline, 3 months, 6 months, and 12 months after surgery

• Mean Change From Baseline in Alveolar Bone Thickness

  Baseline, 3 months, 6 months, and 12 months after surgery

• Three-Dimensional Change in Gingival Soft Tissues

  Baseline, 3 months, 6 months, and 12 months after surgery

• Change in Oral Health-Related Quality of Life Assessed by OHIP-14

  Baseline, 3 months, 6 months, and 12 months after surgery

Study Arms (1)

Esthetic Crown-Lengthening Surgery

EXPERIMENTAL

Participants with excessive gingival display associated with altered passive eruption and alveolar bone involvement will undergo esthetic crown-lengthening surgery consisting of gingivectomy and osseous recontouring. Flap elevation may be performed when indicated according to the periodontal phenotype and local anatomical characteristics.

Procedure: Esthetic Crown-Lengthening Surgery

Interventions

Esthetic Crown-Lengthening Surgery PROCEDURE

Esthetic periodontal surgery will be performed to correct altered passive eruption. Gingival tissue will be removed by an internal bevel gingivectomy. Osseous recontouring will then be performed to establish an adequate relationship between the cementoenamel junction and the alveolar bone crest. Depending on the periodontal phenotype and anatomical characteristics, osseous recontouring may be performed with or without flap elevation.

Esthetic Crown-Lengthening Surgery

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults with an esthetic complaint related to excessive gingival display.
• Diagnosis of altered passive eruption as one of the etiologic factors associated with excessive gingival display.
• Altered passive eruption involving the alveolar bone.

You may not qualify if:

• Current orthodontic treatment.
• Active periodontal disease.
• Systemic conditions that contraindicate periodontal surgical procedures, including uncontrolled autoimmune diseases.
• Use of medications that may interfere with the inflammatory response or wound healing, including corticosteroids or immunosuppressive agents.
• Current smokers.
• Former smokers who discontinued smoking less than 12 months before enrollment.
• Pregnant or breastfeeding individuals.
• Excessive gingival display primarily associated with lip hypermobility or vertical maxillary excess without concomitant altered passive eruption.

Sponsors & Collaborators

• University of Sao Paulo: lead

Study Sites (1)

School of Dentistry of Ribeirão Preto, University of Sao Paulo

Ribeirão Preto, São Paulo, 14040-904, Brazil

RECRUITING

Central Study Contacts

Edgar Daniel Vargas Quiroga, DDS, MSc

CONTACT

+5511982499298; edgar.vargasquiroga@usp.br

Arthur Belem Novaes Jr, DDS, PhD

CONTACT

novaesjr@forp.usp.br

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Model Details: All participants will receive the same esthetic periodontal surgical intervention and will be followed longitudinally for 12 months. Outcomes will be compared with each participant's baseline measurements.

Study Record Dates

• First Submitted: August 8, 2026
• First Posted: August 13, 2026
• Study Start: August 10, 2026
• Primary Completion (Estimated): February 1, 2028
• Study Completion (Estimated): February 1, 2028
• Last Updated: August 17, 2026

Record last verified: 2026-08

Locations

BR (1)