NCT07756320

Brief Summary

The goal of this observational study is to 1) better understand and predict biological processes before disease begins or is identified, 2) study genomic and environmental contributors to disease, 3) identify ways to stop disease advancement before it becomes serious or complex, and 4) identify potential targets for disease therapy. Participants will be asked to:

  • collect biological samples

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100,000

participants targeted

Target at P75+ for all trials

Timeline
113mo left

Started Aug 2026

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
enrolling by invitation

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 28, 2026

Completed
10 days until next milestone

Study Start

First participant enrolled

August 7, 2026

Completed
3 days until next milestone

First Posted

Study publicly available on registry

August 10, 2026

Completed
4.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2030

Expected
5 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2035

Last Updated

August 10, 2026

Status Verified

August 1, 2026

Enrollment Period

4.3 years

First QC Date

July 28, 2026

Last Update Submit

August 7, 2026

Conditions

Exposure, EnvironmentalGenetic Predisposition

Outcome Measures

Primary Outcomes (1)

  • Build a comprehensive, multi-omics and phenotype data and biorepository.

    Up to 5 years

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Mayo Clinic patients

You may qualify if:

  • Age ≥ 18 years
  • Registered Mayo Clinic patient
  • Able to provide informed consent

You may not qualify if:

  • Other co-morbidity that, in physician's opinion, would interfere with patient's ability to participate in the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States

Location

Biospecimen

Retention: SAMPLES WITH DNA

Blood

MeSH Terms

Conditions

Genetic Predisposition to Disease

Condition Hierarchy (Ancestors)

Disease SusceptibilityDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Konstantinos N. Lazaridis, M.D.

    Mayo Clinic

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
ECOLOGIC OR COMMUNITY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Executive Director, Center for Individualized Medicine

Study Record Dates

First Submitted

July 28, 2026

First Posted

August 10, 2026

Study Start

August 7, 2026

Primary Completion (Estimated)

December 1, 2030

Study Completion (Estimated)

December 1, 2035

Last Updated

August 10, 2026

Record last verified: 2026-08

Locations

US(1)