NCT07756021

Brief Summary

Chronic Non-Specific Low Back Pain is the pain with tension, soreness or stiffness of lower back muscles lasting from 3 months or longer due to off unidentifiable cause. Low back pain (LBP), one of the most common musculoskeletal disorders seen in the general population and has effect on every age group. The objective of the study is to compare effects of positional and active release technique on pain and flexibility among chronic non-specific low back pain patients. This study was a Randomized Clinical trial and was conducted at Arif Memorial teaching hospital. A sample size of Total 30 patients was taken in this study using a consecutive sampling technique. Patients were randomly assigned into two groups. Group A was treated with positional release therapy (PRT) and Group B was treated with active release therapy (ART). Then the evaluation was done on day one as pre-treatment values and post treatment values were assessed after receiving the treatment session of 6 days for 2 consecutive weeks. The collected data was analyzed on SPSS 25. By using the Shapiro-wilk test found that the data was normally distributed with a p-value\>0.05. By using paired t-test it has been that both techniques show significant results are effective for treating chronic non-specific low back pain. Using independent t-test with p-value\<0.05 it has been found that Positional Release Technique being superior to Active Release Technique with p-value\<0.05 by bringing the reduced flexibility to near normal and pain to the lowest level. The results suggest that both Active Release Technique and Positional Release Technique are effective in reducing the pain and improving the flexibility of the muscles in patients with Chronic non-specific low back pain. But Positional Release Technique has shown significant reduction in pain and increasing the flexibility of the muscles thus considered to be more effective than Active Release Technique.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Aug 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 8, 2025

Completed
2 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 10, 2025

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

January 10, 2026

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

August 5, 2026

Completed
5 days until next milestone

First Posted

Study publicly available on registry

August 10, 2026

Completed
Last Updated

August 10, 2026

Status Verified

August 1, 2026

Enrollment Period

2 days

First QC Date

August 5, 2026

Last Update Submit

August 5, 2026

Conditions

Keywords

Active release therapy (ART)Chronic non-specific Low back painPositional release therapy (PRT)flexibility

Outcome Measures

Primary Outcomes (5)

  • Numerical Pain Rating Scale

    It is used to assess pain

    Pre and post 2 weeks

  • Active Knee Extension Test

    It is used to assess Hamstring Flexibility

    Pre and Post 2 weeks

  • Flexion, Adduction, and Internal Rotation (FAIR) Test

    It is used to measure Piriformis Flexibility

    Pre and 2 weeks post intervention

  • Thomas Test

    It is used to measure Iliopsoas Flexibility

    Pre and Post 2 weeks intervention

  • Ankle Dorsiflexion Test

    It is used to assess Gastrocnemius Flexibility

    Pre and 2 week Post intervention

Study Arms (2)

Baseline treatment + Positional Release Technique

EXPERIMENTAL
Other: Baseline Treatment + Positional Release Therapy

Baseline treatment + Active Release Technique

ACTIVE COMPARATOR
Other: Baseline treatment + Active Release Therapy

Interventions

Baseline treatment: Hot pack for 10 mins Positional Release Therapy: For Hamstring, Piriformis, Gastrocnemius and Iliopsoas

Baseline treatment + Positional Release Technique

Baseline treatment: Hot pack for 10 mins Active Release Therapy: For Hamstring, Piriformis, Gastrocnemius and Iliopsoas

Baseline treatment + Active Release Technique

Eligibility Criteria

Age20 Years - 40 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Patients with Low Back Pain (for more than 3 months) with Mild and Moderate Intensity, Tenderness over Low Back, Buttocks and Hip Joint

You may not qualify if:

  • Patients with Inflammatory Conditions (RA, Ankylosing Spondylosis)
  • Patients with previous history of surgery around Hip and Knee
  • Patients with Peripheral Vascular Disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Arif Memorial Teaching Hospital

Lahore, 54600, Pakistan

Location

Related Publications (6)

  • Javed Z, Safdar M. Comparative effects of post isometric relaxation and active release technique of calf muscles in young females; Randomized Clinical Trial. J Pak Med Assoc. 2026 Mar;76(3):353-357. doi: 10.47391/JPMA.22142.

  • Palermo M, Reich S, Rives M. The Effect of Active Release Technique on Hamstring Extensibility: A Critically Appraised Topic. J Sport Rehabil. 2024 Jan 30;33(3):202-207. doi: 10.1123/jsr.2023-0229. Print 2024 Mar 1.

  • Alarab A, Daoud R, Hegazy MM. Positional Release Technique Versus Muscle Energy Technique for Patients With Nonspecific Low Back Pain With Facet Joint Restriction: A Pilot Randomized Comparative Study. Pain Res Manag. 2026;2026(1):e9964889. doi: 10.1155/prm/9964889.

  • Yadav R, Sharma S. Efficacy of Myofascial Release Therapy and Positional Release Therapy in Patients with Upper Trapezius Trigger Points: Study Protocol of a Double-blinded Randomized Clinical Trial. Int J Ther Massage Bodywork. 2024 Dec 12;17(4):49-57. doi: 10.3822/ijtmb.v17i4.1041. eCollection 2024 Dec.

  • Sultatos LG, Minor LD. Biotransformation of paraoxon and p-nitrophenol by isolated perfused mouse livers. Toxicology. 1985 Aug;36(2-3):159-69. doi: 10.1016/0300-483x(85)90051-4.

  • Danazumi MS, Zakari UU, Yakasai AM, Speicher TE, Dermody G, Hassan AB. Positional release technique in the management of low back pain: A systematic review and meta-analysis. J Bodyw Mov Ther. 2025 Oct;44:295-311. doi: 10.1016/j.jbmt.2025.05.021. Epub 2025 May 13.

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Senior Lecturer

Study Record Dates

First Submitted

August 5, 2026

First Posted

August 10, 2026

Study Start

August 8, 2025

Primary Completion

August 10, 2025

Study Completion

January 10, 2026

Last Updated

August 10, 2026

Record last verified: 2026-08

Locations