Recovery Opportunities Through Ongoing Treatment Sustainment

NCT07746401 | Not Yet Recruiting DMC

• 2 other identifiers: 23421K23DA065849-01
• Study Type: interventional
• Target: 60
• Locations: 0 countries
• Sites: N/A

Brief Summary

Adolescents in rural communities face limited access to effective substance use services, increasing their risk for opioid and other substance use disorders. This project will use an adaptive, iterative implementation approach to improve the integration of external substance use service providers into rural school settings. Findings will inform strategies to integrate and scale adolescent substance use services in schools. Support for this trial is provided by the HEAL Initiative (https://heal.nih.gov/).

Conditions

Substance Use Disorders (SUDs)

Keywords

Substance-Related Disorders; School Behavioral Health; Rural Behavioral Health

Outcome Measures

Primary Outcomes (4)

• Reach and Engagement

  Reach and Engagement will be tracked through service logs, including the number of students referred, completed referrals, and retention in care.

  From enrollment to 90-day follow-up

• 90-day Substance Use Self Report

  The timeline followback will be used to assess self-reported substance use frequency

  Measured from baseline to 90-day follow-up

• 90-Day Substance Use Urinalysis

  Substance use will be assessed using urinalysis.

  Measured from baseline to 90-day follow-up.

• Opioid-related knowledge and likelihood to engage in misuse behaviors

  Opioid-related knowledge and likelihood to engage in misuse behaviors will be assessed with the Adolescent Opioid Safety and Learning scale

  Assessed from baseline to 90-day follow-up

Secondary Outcomes (3)

• Motivation for substance use and problems associated

  Assessed between the baseline assessment and 90-day follow-up

• Depressive Symptoms

  Assessed between the baseline assessment and 90-day follow-up

• Anxiety Symptoms

  Assessed from baseline to 90-day follow-up.

Study Arms (1)

Youth Substance Use Unit

EXPERIMENTAL

The YSU provides adolescents access to several evidence-based interventions, including access to an on-site substance use counselor trained in evidence-based practices for adolescent SUD, peer recovery specialists, and, if indicated, virtual access to an OUD treatment provider and/or clinical psychologist for more acute and co-occurring disorder treatment.

Behavioral: Youth Substance Use Unit

Interventions

Youth Substance Use Unit BEHAVIORAL

The YSU provides adolescents access to several evidence-based interventions, including access to an on-site substance use counselor trained in evidence-based practices for adolescent SUD, peer recovery specialists, and, if indicated, virtual access to an OUD treatment provider and/or clinical psychologist for more acute and co-occurring disorder treatment.

Youth Substance Use Unit

Eligibility Criteria

• Age: 13 Years - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Are enrolled in one of the participating schools
• Are referred or independently access YSU services;
• Are above age of 13

You may not qualify if:

• Demonstrating active, unstable or untreated psychiatric symptoms, including mania and/or psychosis that would interfere with study participation
• Inability to understand the study and provide informed consent in English

Sponsors & Collaborators

• University of Maryland, College Park: lead
• National Institute on Drug Abuse (NIDA): collaborator

MeSH Terms

Conditions

Substance-Related Disorders

Condition Hierarchy (Ancestors)

Chemically-Induced Disorders; Mental Disorders

Study Officials

• Noah S Triplett, PhD

  University of Maryland, College Park

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Noah S Triplett, PhD

CONTACT

(301) 405-5862; ntrip7@umd.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: This study builds on an innovative community partnership, the Youth Substance Use Unit (YSU), which serves adolescents with substance use problems at high schools on the Eastern Shore of Maryland. The YSU provides adolescents access to several evidence-based interventions, including access to an on-site substance use counselor trained in evidence-based practices for adolescent SUD, peer recovery specialists, and, if indicated, virtual access to an OUD treatment provider and/or clinical psychologist for more acute and co-occurring disorder treatment.

Study Record Dates

• First Submitted: July 29, 2026
• First Posted: August 5, 2026
• Study Start: August 1, 2026
• Primary Completion (Estimated): June 1, 2030
• Study Completion (Estimated): June 1, 2031
• Last Updated: August 5, 2026

Record last verified: 2026-07

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, ANALYTIC CODE
• Time Frame: Data will be made available no later than the time of first publication or the end of the performance period, whichever comes first. Data will be retained and available for a minimum of 10 years in accordance with NIH expectations.
• Access Criteria: Data will be submitted to the National Addiction and Health Data Archive Program in alignment with the HEAL Data Sharing Policy. Within one year of award, the study will be registered on the HEAL platform, including submission of HEAL-specific study-level metadata. Public-facing datasets will be assigned a persistent unique identifier (e.g., DOI) and indexed for searchability. Data will be made available no later than the time of first publication or the end of the performance period, whichever comes first. Data will be retained and available for a minimum of 10 years in accordance with NIH expectations.