Efficacy of Seated Exercise on Functional Capacity and Quality of Life in Patients With Leukemia During Chemotherapy Cycles

NCT07740174 | Not Yet Recruiting

• 1 other identifier: seated exercises in leukemia
• Study Type: interventional
• Target: 30
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study aims to evaluate the efficacy of seated exercise on functional capacity and quality of life in patients with leukemia during chemotherapy cycles Participants will receive efficacy of seated exercise on functional capacity and quality of life in patients with leukemia during chemotherapy cycles over a defined period. Outcomes will be assessed using Pulmonary function test, 6 min walk test and FACT- G questionnaire to determine improvements in quality of life in cancer patient rehabilitation special to diagnosed with leukemia.

Conditions

Leukemia

Keywords

seated exercise, Functional capacity, Quality of life, Chemotherapy, Exercise therapy

Outcome Measures

Primary Outcomes (2)

• change in functional capacity

  Functional capacity will be assessed by the six-minute walk test (6MWT) distance before and after the four week seated exercise programe.

  Baseline and after 4 weeks of intervention

• change in quality of life

  Quality of life will be assessed using the FACT-G questionnaire before and after the four week seated exercise programe

  Baseline and after 4 weeks of intervention

Secondary Outcomes (1)

• Change in Maximum Voluntary Ventilation (MVV)

  Baseline and after 4 weeks of intervention

Study Arms (2)

Seated exercise group

EXPERIMENTAL

Behavioral: Seated exercise

control group

NO INTERVENTION

Interventions

Seated exercise BEHAVIORAL

Participants in the intervention group will perform a structured seated exercise program during their chemotherapy cycles. The exercise program will consist of supervised, individualized seated exercises designed to improve functional capacity and quality of life. The exercise sessions will be performed according to the study protocol throughout the intervention period. Each session will consist of a five-minute warm up, 20 minutes of moderate intensity repetitive motion exercises, and a five -minute cool-down. Functional outcomes will be assessed before and after the exercise program. including maximum voluntary ventilation , six-minute walk test distance, and FACT- G quesionnaire.

Seated exercise group

Eligibility Criteria

• Age: 30 Years - 40 Years
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Male patients with age ranges from 30 to 40 years.
• All patients in this study will be on chemotherapy from at least one cycle as a treatment of leukemia.
• All patients will be hemodynamically stable.
• Patients are ambulant.

You may not qualify if:

• Lung cancer
• History of any pulmonary disease.
• Metastasis of lung , ribs and mediastinal structure.
• Pulmonary pathology (e.g. acute respiratory distress syndrome, or exacerbation of chronic obstructive pulmonary disease).
• Ruptured eardrum or any other condition of the ear.
• Severe bronchospasm.
• High peak air way pressure (barotraumas).
• patients with marked elevated left ventricular end- diastolic volume and pressure.
• patients with worsening haert failure signs and symptoms.

Sponsors & Collaborators

• Suez University: lead

MeSH Terms

Conditions

Leukemia

Condition Hierarchy (Ancestors)

Neoplasms by Histologic Type; Neoplasms; Hematologic Diseases; Hemic and Lymphatic Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of physical therapy for general surgery, Burn and skin, Suez university, Suez ,Egypt

Study Record Dates

• First Submitted: July 28, 2026
• First Posted: July 31, 2026
• Study Start: August 1, 2026
• Primary Completion (Estimated): November 1, 2026
• Study Completion (Estimated): December 1, 2026
• Last Updated: July 31, 2026

Record last verified: 2026-07