Bilateral Modified Thoracoabdominal Nerve Block as an Analgesic Technique in Comparison With Bilateral Thoracic Erector Spinae Plane Block in Abdominoplasty Operations

NCT07738900 | Completed

• 1 other identifier: MD.24.11917
• Study Type: interventional
• Target: 48
• Locations: 1 country
• Sites: 1

Brief Summary

This study aimed to compare the analgesic effect of bilateral ultrasound-guided modified thoracoabdominal nerve block with bilateral ultrasound-guided erector spinae plane block in abdominoplasty surgery.

Conditions

Modified Thoracoabdominal Nerve Block (M-TAPA); Analgesic Technique; Thoracic Erector Spinae Plane Block; Abdominoplasty

Outcome Measures

Primary Outcomes (1)

• Total opioid consumption

  Intravenous pethidine (0.5mg/kg) was taken every 12 hours as rescue analgesia.

  24 hours postoperatively

Secondary Outcomes (5)

• Duration of analgesia

  24 hours postoperatively

• Degree of pain

  24 hours postoperatively

• Cortisol level

  24 hours postoperatively

• C-reactive protein (CRP) level

  24 hours postoperatively

• Incidence of complications

  24 hours postoperatively

Study Arms (3)

Control group

ACTIVE COMPARATOR

Patients received only standard general anesthesia.

Drug: General Anaesthesia using intravenous propofol, fentanyl intravenous, and atracurium besylate

Modified thoracoabdominal nerve block group

EXPERIMENTAL

Patients received modified thoracoabdominal nerve block bilaterally

Drug: Modified thoracoabdominal nerve block using 25 mL of bupivacaine 0.25%

Erector spinae plane block group

EXPERIMENTAL

Patients received an erector spinae plane block bilaterally.

Drug: Erector spinae plane block using 25 mL of bupivacaine 0.25%

Interventions

General Anaesthesia using intravenous propofol, fentanyl intravenous, and atracurium besylate DRUG

Patients received only standard general anesthesia using intravenous propofol (2-3 mg/kg), fentanyl intravenous (1.5µ/kg) and atracurium besylate (0.6 mg/kg).

Control group

Modified thoracoabdominal nerve block using 25 mL of bupivacaine 0.25% DRUG

Patients received modified thoracoabdominal nerve block bilaterally using 25 mL of bupivacaine 0.25% and a lidocaine mixture (15 mL of bupivacaine 0.5% plus 5 mL of 2% lidocaine).

Modified thoracoabdominal nerve block group

Erector spinae plane block using 25 mL of bupivacaine 0.25% DRUG

Patients receive erector spinae plane block bilaterally using 25 mL of bupivacaine 0.25% and a lidocaine mixture (15 mL of bupivacaine 0.5% plus 5 mL of 2% lidocaine).

Erector spinae plane block group

Eligibility Criteria

• Age: 21 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Age between 21 and 60 years.
• Both sexes.
• American Society of Anesthesiologists physical status grade I and grade II.
• Elective abdominoplasty operation.

You may not qualify if:

• Patient refusal.
• Local skin infection and sepsis at site of the block.
• Known allergy to local anesthetic drugs.
• Coagulopathy.
• Psychiatric diseases.
• Central or peripheral neurological disease.

Sponsors & Collaborators

• Mansoura University: lead

Study Sites (1)

Mansoura University

Al Mansurah, Dakahlia Governorate, 35516, Egypt

Location

MeSH Terms

Interventions

Atracurium

Intervention Hierarchy (Ancestors)

Benzylisoquinolines; Isoquinolines; Heterocyclic Compounds, 2-Ring; Heterocyclic Compounds, Fused-Ring; Heterocyclic Compounds

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Lecturer of Anesthesia and Surgical Intensive Care, Mansoura University, Egypt.

Study Record Dates

• First Submitted: July 25, 2026
• First Posted: July 31, 2026
• Study Start: December 1, 2024
• Primary Completion: June 30, 2026
• Study Completion: June 30, 2026
• Last Updated: July 31, 2026

Record last verified: 2026-07

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: After the end of study for one year.
• Access Criteria: The data will be available upon a reasonable request from the corresponding author.

Locations

EG (1)