Single _ Drill Vs Full Sequence Guided Implant Placement

NCT07737197 | Completed

• 1 other identifier: Guided-Implant-RCT-2026
• Study Type: interventional
• Target: 16
• Locations: 1 country
• Sites: 1

Brief Summary

This randomized clinical trial aims to compare the accuracy of single-drill (pilot-guided) computer-guided implant surgery versus full-sequence computer-guided dental implant placement. The study evaluates clinical and radiographic outcomes, focusing on apical, angular, coronal, and depth linear deviations using post-operative cone-beam computed tomography (CBCT) superimposition.

Conditions

Tooth Loss; Partial Edentulism

Keywords

implant; Dental Implants; Computer-Guided Surgery; Pilot-Guided Surgery

Outcome Measures

Primary Outcomes (1)

• Apical deviation

  The linear deviation between the planned and actual implant apex position measured on post-operative CBCT superimposition.

  Immediately after surgery (Post-operative CBCT).

Study Arms (2)

Full Sequence Computer Guidance

EXPERIMENTAL

Patients undergo dental implant placement using full-sequence computer guidance, where implant site preparation and insertion are accomplished using all sequential drills and metal reducers with the surgical guide.

Procedure: Full-sequence computer-guided dental implant placement.

Single Drill / Pilot-Guided Computer Guidance

ACTIVE COMPARATOR

Patients undergo dental implant placement using first-drill (pilot-guided) computer guidance, where the initial pilot osteotomy is performed through the surgical guide, followed by removal of the guide and completion of the remaining sequential drilling and implant placement freehand.

Procedure: Single-drill computer-guided dental implant placement

Interventions

Full-sequence computer-guided dental implant placement. PROCEDURE

Dental implant placement using full sequence computer guidance with all sequential drills and metal reducers

Full Sequence Computer Guidance

Single-drill computer-guided dental implant placement PROCEDURE

Dental implant placement using first-drill (pilot-guided) computer guidance, followed by freehand sequential drilling and placement

Single Drill / Pilot-Guided Computer Guidance

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age \>= 18 years, both sexes
• Patients requiring dental implant placement in the posterior region (molar area)
• Patients systemically healthy with no medical history contraindicating implant surgery
• Sufficient inter-arch space for future prosthesis (minimum 7 mm)

You may not qualify if:

• Bone height \< 6 mm at the proposed implant site
• Inadequate oral hygiene
• Heavy smoking (\>10 cigarettes/day)
• Alcohol or drug abuse
• Pregnancy
• Local or systemic infection
• Uncontrolled metabolic disease (e.g., diabetes mellitus)
• Severe hepatic or renal dysfunction
• Chemotherapy or radiotherapy within the last 5 years
• Immunosuppression therapy or autoimmune disorders
• Complete edentulism
• Pathological conditions such as periapical or periodontal abscesses
• Untreated gingivitis or periodontitis

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Faculty of Dentistry, Cairo University

Cairo, Egypt

Location

MeSH Terms

Conditions

Tooth Loss

Condition Hierarchy (Ancestors)

Periodontal Diseases; Mouth Diseases; Stomatognathic Diseases; Tooth Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: DENTIST

Study Record Dates

• First Submitted: July 27, 2026
• First Posted: July 30, 2026
• Study Start: September 10, 2025
• Primary Completion: July 10, 2026
• Study Completion: July 10, 2026
• Last Updated: July 31, 2026

Record last verified: 2026-07

Locations

EG (1)