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Postoperative Analgesic Outcomes After Bilateral Ultrasound-Guided Transversalis Fascia Plane Block With or Without Dexamethasone in Cesarean Delivery: A Retrospective Cohort Study
Sponsor study identifier
observational
93
1 country
1
Study Start
August 3, 2026
Actual (reported)Primary Completion
August 17, 2026
Actual (reported)Study Completion
August 17, 2026
Actual (reported)Cesarean delivery is one of the most frequently performed surgical procedures worldwide, and effective postoperative pain management is essential to facilitate early mobilization, maternal-infant bonding, breastfeeding, and overall recovery. Ultrasound-guided transversalis fascia plane block (TFPB) has become an increasingly utilized component of multimodal analgesia following cesarean delivery because it provides effective somatic analgesia of the lower anterior abdominal wall. Adjuvants such as dexamethasone are frequently added to local anesthetics with the aim of prolonging block duration and improving postoperative analgesia; however, evidence regarding the clinical benefits of dexamethasone as an adjunct in TFPB remains limited. At our institution, bilateral ultrasound-guided TFPB is routinely performed for postoperative analgesia in patients undergoing cesarean delivery under spinal anesthesia, provided there is no contraindication and informed consent has been obtained. According to the treating anesthesiologist's routine clinical preference, dexamethasone may be added to the local anesthetic solution in some patients, whereas others receive local anesthetic alone. This retrospective cohort study will review the medical records and postoperative follow-up forms of patients who underwent cesarean delivery between November 1, 2025, and June 30, 2026. Postoperative analgesic outcomes, including opioid consumption, pain scores, time to first analgesic request, postoperative nausea and vomiting, recovery quality, and block-related adverse events, will be compared between patients receiving bilateral TFPB with dexamethasone and those receiving bilateral TFPB without dexamethasone. The findings are expected to provide real-world evidence regarding the potential contribution of dexamethasone to the analgesic efficacy of bilateral TFPB following cesarean delivery.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
August 17, 2026
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
July 27, 2026
Actual (reported)July 30, 2026
Actual (reported)August 3, 2026
Actual (reported)August 17, 2026
Actual (reported)August 17, 2026
Actual (reported)Cumulative opioid consumption during the first 24 postoperative hours
Total opioid consumption delivered through the patient-controlled analgesia device during the first 24 hours after surgery, expressed in mg. Patients were instructed to use the PCA device when the Numeric Rating Scale pain score was 4 or higher.
First 24 hours after surgery
Postoperative pain intensity
1, 3, 6, 9, 12, 18, and 24 hours after surgery
Time to first analgesic request
Within the first 24 postoperative hours
Quality of postoperative recovery
24 hours after surgery
Patients who received bilateral ultrasound-guided transversalis fascia plane block with 25 mL of 0.25% bupivacaine per side plus 8 mg dexamethasone for postoperative analgesia following cesarean delivery under spinal anesthesia.
Patients who received bilateral ultrasound-guided transversalis fascia plane block with 25 mL of 0.25% bupivacaine per side for postoperative analgesia following cesarean delivery under spinal anesthesia.
Adult women who underwent elective cesarean delivery under spinal anesthesia and received bilateral ultrasound-guided transversalis fascia plane block with or without dexamethasone for postoperative analgesia between November 1, 2025, and June 30, 2026, at our institution.
Bahcesehir Unişversity Medicalpark Goztepe hospital
Istanbul, Turkey (Türkiye)
Cadirci DY, Aydin ME, Ahiskalioglu EO, Celik EC, Yayik AM, Coruh S, Senocak GNC, Ciftci B, Ahiskalioglu A. Intrathecal morphine versus transversalis fascia and transversus abdominis plane blocks combination on obstetric quality of recovery after cesarean delivery: a randomized controlled trial. BMC Anesthesiol. 2025 Dec 17;26(1):46. doi: 10.1186/s12871-025-03559-0.
Dost B, DE Cassai A, Bugada D, Balzani E, Karapinar YE, Beldagli M, Ozkal Yalin MS, Tulgar S, Ahiskalioglu A. The analgesic effect of transversalis fascia plane block after cesarean delivery: a systematic review and meta-analysis with trial sequential analysis. Minerva Anestesiol. 2025 Jun;91(6):564-572. doi: 10.23736/S0375-9393.25.18771-3.
93 participants (actual enrollment reported by the registry).
First Submitted
July 27, 2026
First Posted
July 30, 2026
Study Start
August 3, 2026
Actual (reported)Contact the study team to confirm eligibility.
Primary Completion
August 17, 2026
Actual (reported)Study Completion
August 17, 2026
Actual (reported)Last Updated
August 18, 2026
Record last verified: 2026-08
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