OSAHS Screening in Diverse Populations

NCT07736872 | Recruiting DMC

• 2 other identifiers: ES-2024-169-01202201020586
• Study Type: observational
• Target: 100,000
• Locations: 1 country
• Sites: 2

Brief Summary

The goal of this prospective observational study is to learn about the current prevalence of obstructive sleep apnea-hypopnea syndrome in community population, patients with specific diseases and special population from China. The main question it aims to answer is: (1) What are the prevalence and clinical characteristics of OSA in the community population, the specific disease population and the special population respectively? (2) How about the application value of each OSA screening questionnaire for different populations？Participants will all complete a screening questionnaire, and some will be selected by random sampling to complete either a polysomnography (PSG) or a portable sleep monitor (PM).

Conditions

Obstructive Sleep Apnea (OSA); Snoring; Prevalence; Questionnaires and Surveys

Keywords

osbtructive sleep apnea; snoring; prevalence; screening questionnaires; CNCQ-OSA; STOP-Bang; NoSAS

Outcome Measures

Primary Outcomes (2)

• Apnea-Hypopnea Index (AHI)

  Collected from polysomnography (PSG) or home sleep apnea testing (PM) for the diagnosis of obstructive sleep apnea (OSA). Unit of Measure: events/hour

  Baseline

• Lowest Oxygen Saturation (Lowest SpO₂)

  Collected from PSG or PM to evaluate nocturnal hypoxemia. Unit of Measure: %

  Baseline

Secondary Outcomes (3)

• Diagnostic Value of the CNCQ-OSA Questionnaire

  Baseline

• Diagnostic Value of the STOP-Bang Questionnaire

  Baseline

• Diagnostic Value of the NoSAS Score

  Baseline

Study Arms (3)

community population

registered community populations aged 18-80 years old.

patients with specific diseases

patients with hypertension, diabetes, cardiovascular and cerebrovascular diseases, chronic obstructive pulmonary disease, asthma and other OSA related comorbidities, aged 18-80 years old.

Other: patients with hypertension, diabetes, cardiovascular and cerebrovascular diseases, chronic obstructive pulmonary disease, asthma and other OSA related comorbidities.

special population

Including college teachers and students, doctors and nurses, and company employees, aged 18-80 years old.

Interventions

patients with hypertension, diabetes, cardiovascular and cerebrovascular diseases, chronic obstructive pulmonary disease, asthma and other OSA related comorbidities. OTHER

In order to explore the prevalence of OSA in patients with different comorbid diseases, this study set up this observation group.

patients with specific diseases

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Target participants were recruited from multiple centers: Community population: A random number table method is used to select several communities within the designated research area. The research team then obtains a complete list of registered residents in these communities as the sampling frame. A computer-based random number generator is utilized to randomly select target residents. Patients with specific diseases: hypertension, diabetes, cardiovascular and cerebrovascular diseases, chronic obstructive pulmonary disease, asthma and other OSA related comorbidities. Special population: Including college teachers and students, doctors and nurses, and company employees.

You may qualify if:

• Sign the informed consent form before participating in the study
• Complete independent behaviour and cognitive abilities
• Ability to answer the questionnaire completely and accurately

You may not qualify if:

• Incomplete answers to the scale
• Patients with severe diseases and acute infections or those requiring long-term home oxygen therapy
• Patients with severe mental and psychological disorders
• Patients with severe organ failure
• patients with a total sleep time \<240 min by PSG or PM

Sponsors & Collaborators

• Kang Wu: lead

Study Sites (2)

The First Affiliated Hospital of Guangzhou Medical University

Guangzhou, Guangdong, China

RECRUITING

Anshun People's Hospital

Anshun, Guizhou, China

NOT YET RECRUITING

MeSH Terms

Conditions

Sleep Apnea, Obstructive; Snoring

Interventions

Blood Circulation

Condition Hierarchy (Ancestors)

Sleep Apnea Syndromes; Apnea; Respiration Disorders; Respiratory Tract Diseases; Sleep Disorders, Intrinsic; Dyssomnias; Sleep Wake Disorders; Nervous System Diseases; Respiratory Sounds; Signs and Symptoms, Respiratory; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Cardiovascular Physiological Phenomena; Circulatory and Respiratory Physiological Phenomena

Study Officials

• Nuofu Zhang, professor

  The First Affiliated Hospital of Guangzhou Medical University

  STUDY DIRECTOR

Central Study Contacts

Donghao Wang, Phd

CONTACT

+86 15622204731; 820512548@qq.com

Dongxing Zhao, professor

CONTACT

rieast@163.com

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: CROSS SECTIONAL
• Target Duration: 2 Days
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Dr

Study Record Dates

• First Submitted: June 6, 2025
• First Posted: July 30, 2026
• Study Start: September 1, 2024
• Primary Completion (Estimated): August 1, 2027
• Study Completion (Estimated): August 1, 2027
• Last Updated: July 30, 2026

Record last verified: 2026-07

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, CSR

Locations

CN (2)