Reconstruction by Thoracodorsal Artery Perforator Flap in Patients With Upper Body Soft Tissue Defects

NCT07734337 | Enrolling By Invitation DMC

• 1 other identifier: Soh-Med-26-6-1MS
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

evaluation of versatility and reliability of thoracodorsal artery perforator flap by assessment of recipient site reach

Conditions

Reconstruction of Upper Body Soft Tissue Defects

Keywords

TDAP flap recipient site reach

Outcome Measures

Primary Outcomes (1)

• Recipient Site Reach

  Measuring of Successful reach to intended recipient site without vascular compromise by centimeters from the pedicle to the recipient site

  12 months recruitment and 6 months follow up

Study Arms (1)

Patients need reconstruction by Thoracodorsal Artery Perforator Flap

OTHER

Reconstruction of Upper Body by Insertion of Thoracodorsal Artery Perforator Flap to fill the Defects

Procedure: Reconstruction

Interventions

Reconstruction PROCEDURE

Harvesting thoracodorsal artery perforator flap and insetting in the recipient sites reachable for this flap

Patients need reconstruction by Thoracodorsal Artery Perforator Flap

Eligibility Criteria

• Age: 5 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients aged 5 to 75 years old
• Both sexes
• Requiring upper body soft tissue reconstruction (e.g. breast, shoulder chest wall, axilla) following oncological resection, trauma, or contracture excision
• Adequate general condition for surgery

You may not qualify if:

• Patients with uncontrolled comorbidities.
• Prior surgery or radiation in the donor region that compromises vascular anatomy.
• Active local infection or poor wound bed vascularity.

Sponsors & Collaborators

• Sohag University: lead

Study Sites (1)

Sohag University

Sohag, Sohag Governorate, 82511, Egypt

Location

Related Links

• Sui X, Qing L, Yu F, Wu P and Tang J. The versatile thoracodorsal artery perforator flap for extremity reconstruction: from simple to five types of advanced applications and clinical outcomes. J orthop surg res. 2023;18(1):973-9.
• Wolff K-D and Hölzle F. Thoracodorsal Artery Perforator Flap. Raising of Microvascular Flaps: A Systematic Approach: Springer; 2025. p. 371-91.
• Homsy C, Theunissen T and Sadeghi A. The Thoracodorsal Artery Perforator Flap: A Powerful Tool in Breast Reconstruction. Plast Reconstr Surg 2022;150(4):755-761.
• Thomsen JB, Rindom MB, Rancati A and Angrigiani C. Thoracodorsal artery flaps for breast reconstruction-the variants and its approach. Arch Plast Surg. 2021;48(1):15-25.
• Busnardo FF, Coltro PS, Olivan MV, Busnardo APV, Ferreira MC. The thoracodorsal artery perforator flap in the treatment of axillary hidradenitis suppurativa: effect on preservation of arm abduction. Plast Reconstr Surg. 2011;128(4):949-953.

MeSH Terms

Interventions

Plastic Surgery Procedures

Intervention Hierarchy (Ancestors)

Surgical Procedures, Operative

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Model Details: Patients who need reconstruction in Arm, axilla, breast and chest

Study Record Dates

• First Submitted: July 18, 2026
• First Posted: July 29, 2026
• Study Start: March 3, 2025
• Primary Completion: March 3, 2026
• Study Completion (Estimated): April 3, 2027
• Last Updated: July 29, 2026

Record last verified: 2026-07

Locations

EG (1)