Early Urinary Catheter Removal in Enhanced Recovery After Surgery for Laparoscopic Hepatectomy

NCT07733609 | Completed

• 1 other identifier: 2025-597-01
• Study Type: interventional
• Target: 212
• Locations: 1 country
• Sites: 1

Brief Summary

The primary aim was to assess the impact of early catheter removal on postoperative urinary function, urinary complications, and recovery milestones.

Conditions

Laparoscopic Liver Lobectomy

Outcome Measures

Primary Outcomes (1)

• Duration of urinary catheter indwelling (hours)

  7 days

Study Arms (2)

Experimental group

EXPERIMENTAL

Procedure: structured multidisciplinary Enhanced Recovery

Control Group

ACTIVE COMPARATOR

Procedure: conventional perioperative care established by the Hepatobiliary Surgery Department

Interventions

structured multidisciplinary Enhanced Recovery PROCEDURE

Participants received a structured multidisciplinary Enhanced Recovery After Surgery (ERAS) program. Key interventions: preoperative education with an ERAS diary, shortened fasting with oral carbohydrate loading, opioid-sparing multimodal anesthesia, normothermia maintenance, and no routine abdominal drainage. Postoperatively, the urinary catheter was removed within 6 hours, with early oral hydration beginning 2 hours postoperatively, assisted ambulation within 6 hours, multimodal analgesia, and restrictive fluid management.

Experimental group

conventional perioperative care established by the Hepatobiliary Surgery Department PROCEDURE

Participants received conventional perioperative care established by the Hepatobiliary Surgery Department, including routine preoperative fasting (≥8 h for solids, ≥6 h for fluids) without carbohydrate loading, standard balanced general anesthesia, routine abdominal drainage, opioid-based analgesia as needed, fasting for 6 hours postoperatively, oral intake initiated on postoperative day (POD) 1, and urinary catheter removal at approximately 24 hours postoperatively (POD 1).

Control Group

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age 18 to 75 years.
• Preoperative diagnosis of benign or malignant liver tumors, with a plan for standard laparoscopic liver lobectomy.
• Liver function classified as Child-Pugh grade A.
• Indocyanine green (ICG) 15-minute retention rate (ICG R15) \< 14%.
• American Society of Anesthesiologists (ASA) physical status classification I-III.
• Normal preoperative urinary function (residual urine volume \< 50 mL).
• Provision of written informed consent.

You may not qualify if:

• Emergency surgery or conversion to an open surgical procedure.
• Concurrent neurogenic bladder or chronic urinary tract infection.
• Planned transfer to the intensive care unit (ICU) following surgery.
• Anticipated intraoperative blood loss exceeding 1000 mL.
• Presence of urethral stricture or complications related to intraoperative catheterization.
• Unwillingness to participate in the trial.

Sponsors & Collaborators

• Yu Zhang: lead

Study Sites (1)

the First Affiliated Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, 400016, China

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Director

Study Record Dates

• First Submitted: July 24, 2026
• First Posted: July 29, 2026
• Study Start: September 1, 2025
• Primary Completion: April 30, 2026
• Study Completion: April 30, 2026
• Last Updated: July 29, 2026

Record last verified: 2026-07

Locations

CN (1)