NCT07725991

Brief Summary

Bronchiectasis is a chronic lung disease characterized by permanent dilation of the bronchi, leading to persistent cough, mucus overproduction, dyspnea and frequent respiratory infections. It is persistent respiratory symptoms and irreversible airway dilation due to chronic inflammation and impaired mucociliary clearance, often resulting from repeated infections or underlying conditions. This conditions leads to chronic cough, sputum production and breathlessness. Pilmonary rehabilitation is recommended as a reliable strategy for respiratory management, leading to improved lung function, reduced dyspnea and enhanced quality of life. Resonant breathing and Qigong exercise are effective in enhancing respiratory function by improving oxygen intake, relaxation and respiratory muscle strength. A randomized controlled trial will be conducted at DHQ Hospital Sheikhupura. Sample size is 46 calculated by epitool sample size calculator Convenient Sampling Technique will be used age 40 to 65 years consent will be obtained from all patients. Patients will be randomly assigned to group A and group B using simple random sampling. Group A will receive resonant breathing training with standard medical treatment. Group B will received combination of resonant breathing and Qigong exercises. Outcome measures include spirometer, MMRC dysnea scale and a quality of life questionnaire BHQ. Study will be completed within 10 months of duration treatment evaluation will be done after 3 weeks of exercise training program data will be processed using SPSS version 25. normality of data will be assessed through the Shapiro-Wilk test to determine the application of either

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
46

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Dec 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 20, 2025

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 25, 2026

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

July 20, 2026

Completed
1 day until next milestone

First Submitted

Initial submission to the registry

July 21, 2026

Completed
3 days until next milestone

First Posted

Study publicly available on registry

July 24, 2026

Completed
Last Updated

July 24, 2026

Status Verified

July 1, 2026

Enrollment Period

1 month

First QC Date

July 21, 2026

Last Update Submit

July 21, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change in St. George's Respiratory Questionnaire (SGRQ)

    \_The primary outcome is the change in quality of life measured using the St. George's Respiratory Questionnaire (SGRQ). Lower scores indicate better quality of life.

    Baseline of 4 weeks

Study Arms (2)

Resonant breathing exercise

EXPERIMENTAL

Resonant breathing training involving slow, paced breathing at an optimal breathing rate to enhance respiratory efficiency, reduce dyspnea, and improve pulmonary function according to the study protocol.

Other: Resonant breathing exercise

Resonant breathing and Qigong exercise

EXPERIMENTAL

A combined intervention involving resonant breathing training performed at a slow, paced respiratory rhythm along with structured Qigong exercises aimed at improving pulmonary function, reducing dyspnea, enhancing physical relaxation, and improving quality of life in patients with bronchiectasis according to the study protocol.

Other: Resonant breathing and Qigong Exercise.

Interventions

Arm A: Resonant Breathing Training Participants received resonant breathing training alone, involving slow and paced breathing at an individualized optimal respiratory rate to improve pulmonary function, reduce dyspnea, and enhance breathing control in patients with bronchiectasis according to the study protocol. Arm B: Qigong with Resonant Breathing Participants received a combined intervention of resonant breathing training along with structured Qigong exercises. This group performed the same resonant breathing protocol as Arm A, with the addition of Qigong movements designed to further improve respiratory efficiency, physical relaxation, and quality of life in patients with bronchiectasis according to the study protocol.

Also known as: Resonant breathing training, Resonant breathing training and Qigong exercise, Resonant breathing and Qigong exercise
Resonant breathing exercise

Arm A: Resonant Breathing Only Participants in this arm received resonant breathing training alone. The intervention involved slow, paced breathing at an optimal rhythm aimed at improving respiratory efficiency, reducing dyspnea, and enhancing pulmonary function according to the study protocol. Arm B: Resonant Breathing + Qigong Participants in this arm received a combination of resonant breathing training and Qigong exercises. Along with the same resonant breathing protocol as Arm A, additional Qigong exercises were performed to further improve respiratory function, dyspnea, physical relaxation, and quality of life in patients with bronchiectasis according to the study protocol.

Also known as: Resonant breathing training, Resonant breathing and Qigong exercise
Resonant breathing and Qigong exercise

Eligibility Criteria

Age40 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adults aged 40 to 65 years
  • Both male and female participants
  • Diagnosed with bronchiectasis confirmed by clinical and radiological findings
  • Clinically stable for at least 4 weeks (no acute exacerbation)
  • Willing and able to participate in breathing and/or Qigong exercise sessions regularly for 3 weeks

You may not qualify if:

  • Individuals who have experienced a recent flare-up of bronchiectasis in the last month.
  • Patients with serious heart, muscle, or nerve disorders that restrict movement
  • Participants already enrolled in other respiratory therapy programs.
  • Those with mental or communication difficulties preventing proper participation.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Riphah International University

Sheikhupura, Punjab Province, Pakistan

Location

Study Officials

  • Tasneem Shahzadi, MS

    Riphah International University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Model Details: A parallel-group randomized trial comparing combined resonant breathing + Qigong exercises vs. standard care in bronchiectasis patients.
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 21, 2026

First Posted

July 24, 2026

Study Start

December 20, 2025

Primary Completion

January 25, 2026

Study Completion

July 20, 2026

Last Updated

July 24, 2026

Record last verified: 2026-07

Data Sharing

IPD Sharing
Will not share

Locations