Effect of Implementing Cough Augmentation Techniques on Weaning Outcomes Among Critically Ill Patients
1 other identifier
interventional
88
1 country
1
Brief Summary
The study aims to determine the effect of implementing cough augmentation techniques on weaning outcomes among critically ill patients
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Jul 2026
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 8, 2026
CompletedFirst Submitted
Initial submission to the registry
July 19, 2026
CompletedFirst Posted
Study publicly available on registry
July 23, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 8, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
November 10, 2026
July 23, 2026
July 1, 2026
3 months
July 19, 2026
July 19, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
weaning success
measured through successful extubating
within 7 days
Study Arms (2)
Interventional group
EXPERIMENTALthe experimental group receive the cough augmentation techniques
conventional group
NO INTERVENTIONreceive the routine care in the unit
Interventions
the lung volume recruitment maneuver via MV was applied with assistant of the attended physician as follows: Use pressure-controlled ventilation and increase end-inspiratory volume (30 or 40 cm H2O for 30 to 40 seconds unless contraindicated) or inspiratory hold for 30 to 40 seconds to promote cough effectiveness. The patient serially inhales a volume of gas without exhalation until maximum insufflation capacity via the ventilator to facilitate breath-holding (if not contraindicated).
Eligibility Criteria
You may qualify if:
- adult intubated patients
- both sex
You may not qualify if:
- patient with facial trauma
- patient with tracheostomy tube
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Faculty of Nursing, Damanhur University
Damanhūr, Egypt
Related Publications (1)
Chatwin M, Wakeman RH. Mechanical Insufflation-Exsufflation: Considerations for Improving Clinical Practice. J Clin Med. 2023 Mar 31;12(7):2626. doi: 10.3390/jcm12072626.
PMID: 37048708BACKGROUND
Related Links
Study Officials
- PRINCIPAL INVESTIGATOR
sahar youness, professor
professor of critical care and emergency nursing
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- SUPPORTIVE CARE
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- faculty member " lecturer"
Study Record Dates
First Submitted
July 19, 2026
First Posted
July 23, 2026
Study Start
July 8, 2026
Primary Completion (Estimated)
October 8, 2026
Study Completion (Estimated)
November 10, 2026
Last Updated
July 23, 2026
Record last verified: 2026-07
Data Sharing
- IPD Sharing
- Will share
- Shared Documents
- STUDY PROTOCOL
- Time Frame
- at January 2026, and will be available for 5 years
- Access Criteria
- any researcher will be able to access the IPD foe study protocol through contacting us
55-d