NCT07712991

Brief Summary

the study find out the effect of oral and intra ligamentary piroxicam on the post endodontic pain . it tell us which one is better among both methods of using piroxicam

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for phase_4

Timeline
Completed

Started May 2023

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 27, 2023

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 26, 2024

Completed
1 day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 27, 2024

Completed
1.6 years until next milestone

First Submitted

Initial submission to the registry

July 13, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

July 20, 2026

Completed
Last Updated

July 20, 2026

Status Verified

July 1, 2026

Enrollment Period

1.5 years

First QC Date

July 13, 2026

Last Update Submit

July 17, 2026

Conditions

Pain ManagementPost Endodontic Pain

Keywords

painendodontic

Outcome Measures

Primary Outcomes (1)

  • pain intensity

    Pain intensity will be measured by Visual Analogue scale(VAS). Patient will advised to rate there pain intensity from 0 to 10 after 12 hours, 24 and 48 hours. So both groups patient will record there pain in number and report to dentist in follow-up visit.

    12, 24,48 hours

Study Arms (2)

intra ligamentry

EXPERIMENTAL

intra ligamentary mode of administration

Other: intra-ligamentary

oral

NO INTERVENTION

oral use of piroxicam

Interventions

intra-ligamentaryOTHER

intra ligamentary mode of piroxicam use

intra ligamentry

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patient diagnosed with irreversible pulpitis
  • Patient have Tooth pain before Root canal treatment

You may not qualify if:

  • Patient already treated with root canal
  • Necrotic Tooth

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Pakistan Institute of Medical Sciences

Islamabad, Pakistan

Location

Related Publications (1)

  • . Comparing the efficacy of local intraligamentary injection of dexamethasone and piroxicam on postoperative pain in mandibular molars with symptomatic irreversible pulpitis

    BACKGROUND

MeSH Terms

Conditions

AgnosiaPain

Condition Hierarchy (Ancestors)

Perceptual DisordersNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
dental surgeon

Study Record Dates

First Submitted

July 13, 2026

First Posted

July 20, 2026

Study Start

May 27, 2023

Primary Completion

November 26, 2024

Study Completion

November 27, 2024

Last Updated

July 20, 2026

Record last verified: 2026-07

Data Sharing

IPD Sharing
Will not share

Locations

PA(1)