Management of Polycystic Ovarian Syndrome-associated Reproductive Dysfunction Through Kefir Supplementation
Managing Polycystic Ovarian Syndrome- Associated Reproductive Dysfunction Through Kefir Supplementation
1 other identifier
interventional
50
1 country
1
Brief Summary
Polycystic ovary syndrome (PCOS) affect around 6-12% of women of age 18-25 years. Kefir contains bioactive compounds such as lactic acid bacteria, yeast, peptides, polysaccharides and organic acids and acts as a good probiotic source.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Jan 2026
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 18, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 18, 2026
CompletedStudy Completion
Last participant's last visit for all outcomes
April 18, 2026
CompletedFirst Submitted
Initial submission to the registry
July 13, 2026
CompletedFirst Posted
Study publicly available on registry
July 17, 2026
CompletedJuly 17, 2026
July 1, 2026
2 months
July 13, 2026
July 13, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Lipid Profile
Blood lipid profile were obtained using fasting blood samples to determine serum total cholesterol, high-density lipoprotein cholesterol (HD L-C), low density lipoprotein cholesterol (LDL-C) and triglycerides.
8 weeks
Secondary Outcomes (2)
FSH (follicle stimulating hormone)
8 weeks
LH (luteinizing hormone)
8 weeks
Other Outcomes (1)
TSH (Thyroid stimulating hormone test)
8 weeks
Study Arms (2)
Control Group
ACTIVE COMPARATORCalorie deficit diet plan
Experimental Group
EXPERIMENTALDiet plan + 250ml kefir water
Interventions
Participants were subjected to use a regular calorie deficit diet plan
Participants were advised to take water 250ml of water kefir per day in their mid-morning snack time for 2 months.
Eligibility Criteria
You may qualify if:
- Females of age 18-25 will be selected.
- Females suffering from amenorrhea or cycle longer then 35days were selected.
- Females with PCOS were selected.
- Females with BMI 18.5-29.9 were selected in this research.
- Females with thyroid issues were selected.
You may not qualify if:
- Pregnant and breast-feeding females were not included.
- Those who smoke were not included.
- Those who consume alcohol were not included.
- Those suffering from endocrine diseases were not be included.
- Those taking lipid- lowering drugs or blood pressure regulating medications were not be included.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
The University of Lahore
Lahore, Pakistan
Related Links
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- SUPPORTIVE CARE
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Clinical Head UIDNS
Study Record Dates
First Submitted
July 13, 2026
First Posted
July 17, 2026
Study Start
January 18, 2026
Primary Completion
March 18, 2026
Study Completion
April 18, 2026
Last Updated
July 17, 2026
Record last verified: 2026-07
Data Sharing
- IPD Sharing
- Will share