Comparative Study of Adherence to Antibiotic Therapy Among Pediatric Patients: Hospital Emergency Department vs. Primary Care Center

NCT07711756 | Not Yet Recruiting DMC

• 1 other identifier: RECHMPL25_0564
• Study Type: observational
• Target: 191
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study was initiated because of the limited litterature available on this topic. The objective was to compare adherence to antibiotic therapy among a pediatric population treated in two healthcare settings in France: the Gignac Health Center, a primary care facility, and the Pediatric Emergency Department of Montpellier University Hospital. This observational study assessed treatment adherence through a telephone questionnaire administered to parents after the theorical end of the treatment.

Conditions

Tonsillitis Acute; Pneumonia - Bacterial; Otitis Media Acute; Cystitis Acute; Sinusitis Bacterial; Pneumonia Atypical; Impetigo

Keywords

compliance - antibiotic - pediatric

Outcome Measures

Primary Outcomes (1)

• Proportion of patients who adhered to the antibiotic prescription provided by the general practitioner (GP) or the emergency physician (University Hospital)

  Treatment adherence was considered satisfactory when at least 80% of the prescribed antibiotic course was taken

  The study period extended from the initial consultation (antibiotic prescription) to 21 days after the prescription, depending on the prescribed treatment duration.

Study Arms (2)

Pediatric patients prescribed antibiotic for acute bacterial infection at the Gignac Health center

Pediatric patients aged 3 months to 16 years presenting with an acute bacterial infection and prescribed an outpatient antibiotic treatment were eligible for inclusion. Parents were contacted by telephone between 15 and 21 days after the antibiotic prescription to assess treatment adherence.

Children prescribed antibiotic for acute bacterial infection at pediatric emergency of Montpellier

Pediatric patients aged 3 months to 16 years presenting with an acute bacterial infection at pediatric emergency department Montpellier University Hospital and prescribed an outpatient antibiotic treatment were eligible for inclusion. Parents were contacted by telephone between 15 and 21 days after the antibiotic prescription to assess treatment adherence.

Eligibility Criteria

• Age: 3 Months - 16 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Pediatric patients presenting to the Gignac Primary Care Health Center or the Pediatric Emergency Department of Montpellier University Hospital with a suspected bacterial infection and considered eligible for an outpatient oral antibiotic prescription.

You may qualify if:

• Children aged 3 months to 16 years
• Receiving an outpatient oral antibiotic prescription
• Diagnosed with an acute bacterial infection

You may not qualify if:

• Unemancipated minors presenting without a parent or legal guardian.
• Refusal to participate after the reflection period
• Parents unable to understand the study information (e.g., language barrier or cognitive impairment)
• Not affiliated with, or not a beneficiary of, a national health insurance scheme
• Pregnant or breastfeeding female participants

Sponsors & Collaborators

• University Hospital, Montpellier: lead

MeSH Terms

Conditions

Pneumonia, Bacterial; Otitis Media; Pneumonia, Mycoplasma; Impetigo

Condition Hierarchy (Ancestors)

Bacterial Infections; Bacterial Infections and Mycoses; Infections; Pneumonia; Respiratory Tract Infections; Lung Diseases; Respiratory Tract Diseases; Otitis; Ear Diseases; Otorhinolaryngologic Diseases; Mycoplasma Infections; Mycoplasmatales Infections; Gram-Negative Bacterial Infections; Staphylococcal Skin Infections; Staphylococcal Infections; Gram-Positive Bacterial Infections; Streptococcal Infections; Skin Diseases, Bacterial; Skin Diseases, Infectious; Skin Diseases; Skin and Connective Tissue Diseases

Study Officials

• Eric E JEZIORSKI, Professor of Medicine at Montp

  Pediatric Emergency Department, Montpellier University Hospital

  STUDY DIRECTOR

Central Study Contacts

Eric E JEZIORSKI, Professor of Medicine

CONTACT

+33627383451; e-jeziorski@chu-montpellier.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 13, 2026
• First Posted: July 17, 2026
• Study Start (Estimated): September 1, 2026
• Primary Completion (Estimated): August 1, 2028
• Study Completion (Estimated): September 1, 2028
• Last Updated: July 17, 2026

Record last verified: 2026-07

Data Sharing

• IPD Sharing: Will not share