NCT07709806

Brief Summary

Stroke is a leading cause of death and disability worldwide. Many stroke survivors face difficulties with daily activities, sleep problems, anxiety, and depression during recovery. Health education videos can help patients learn about rehabilitation, but standard videos often contain too much information and are hard for patients to follow. This study aims to test whether using semiotics - the science of signs and symbols - to redesign health education videos can help stroke patients better comprehend and apply rehabilitation instructions. The study is designed to include 200 stroke patients at Siping Central Hospital in Jilin Province, China. Patients will be randomly assigned to either the semiotic-optimized video group or the standard health education video group. Outcome measures, including activities of daily living, sleep quality, anxiety, depression, and satisfaction with care, will be assessed before and after the intervention to evaluate the effectiveness of the optimized video education model.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
200

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jan 2023

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2023

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2023

Completed
2.5 years until next milestone

First Submitted

Initial submission to the registry

July 8, 2026

Completed
9 days until next milestone

First Posted

Study publicly available on registry

July 17, 2026

Completed
Last Updated

July 17, 2026

Status Verified

July 1, 2026

Enrollment Period

12 months

First QC Date

July 8, 2026

Last Update Submit

July 13, 2026

Conditions

Ischemic Stroke

Keywords

StrokeVideo EducationSemioticsRehabilitationActivities of Daily Living

Outcome Measures

Primary Outcomes (1)

  • Change in Activities of Daily Living (ADL)

    Modified Barthel Index (MBI), The MBI comprises 10 items assessing ADL, with a total score ranging from 0 to 100. Higher scores indicate better independence in daily living activities.

    Baseline and Day 28

Secondary Outcomes (4)

  • Change in Sleep Quality

    Baseline and Day 28

  • Change in Anxiety

    Baseline and Day 28

  • Change in Depression

    Baseline and Day 28

  • Patient Satisfaction

    Day 28

Study Arms (2)

Experimental: Semiotically-Optimized Video Group

EXPERIMENTAL

Participants received semiotically-optimized video-based health education, 28 days, twice daily, 5-8 minutes per session, including music and video feedback.

Behavioral: Semiotically-Optimized Video Education

Active Comparator: Standard Video Group

ACTIVE COMPARATOR

Participants received standard video-based health education, 28 days, routine rehabilitation instructional videos and assistive device guidance.

Behavioral: Standard Video Education

Interventions

Semiotically-Optimized Video EducationBEHAVIORAL

Participants received semiotically-optimized video-based health education, 28 days, twice daily, 5-8 minutes per session, including music and video feedback.

Experimental: Semiotically-Optimized Video Group
Standard Video EducationBEHAVIORAL

Participants received standard video-based health education, 28 days, routine rehabilitation instructional videos and assistive device guidance.

Active Comparator: Standard Video Group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Imaging-confirmed cerebral infarction per 2019 Chinese Guidelines
  • Age ≥18 years
  • Stable condition during rehabilitation phase
  • Alert, able to comprehend and operate video playback
  • Signed informed consent

You may not qualify if:

  • Incomplete records, inaccurate data, or failure to complete the intervention

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Siping Central People's Hospital

Siping, Jilin, 136000, China

Location

MeSH Terms

Conditions

Ischemic StrokeStroke

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Study Officials

  • Yang Liu, PhD

    Xiamen University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

July 8, 2026

First Posted

July 17, 2026

Study Start

January 1, 2023

Primary Completion

December 31, 2023

Study Completion

December 31, 2023

Last Updated

July 17, 2026

Record last verified: 2026-07

Locations

CN(1)