NCT07708298

Brief Summary

Flexor tendon repair is commonly performed to restore hand function after tendon injuries. Different rehabilitation techniques are used to improve range of motion, grip strength, and functional outcomes. This randomized controlled trial compares the effects of myofascial release and hand mobilization following flexor tendon repair. Thirty participants are randomly allocated into two groups. Outcomes include wrist range of motion, grip strength, and the QuickDASH questionnaire. The findings may help determine the effectiveness of these rehabilitation techniques following flexor tendon repair.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Apr 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2026

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2026

Completed
1 day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 2, 2026

Completed
6 days until next milestone

First Submitted

Initial submission to the registry

July 8, 2026

Completed
8 days until next milestone

First Posted

Study publicly available on registry

July 16, 2026

Completed
Last Updated

July 16, 2026

Status Verified

July 1, 2026

Enrollment Period

3 months

First QC Date

July 8, 2026

Last Update Submit

July 14, 2026

Conditions

Flexor Tendon Injury

Keywords

Flexor tendon repairMyofascial releaseHand mobilizationPhysical therapyRange of motionGrip strengthQuickDASHHand rehabilitation

Outcome Measures

Primary Outcomes (3)

  • Wrist Range of Motion

    Wrist flexion, extension, radial deviation, and ulnar deviation measured using a universal goniometer.

    Baseline (pre-intervention) and 4 weeks

  • Grip Strength

    Grip strength measured using a hand dynamometer.

    Baseline (pre-intervention) and 4 weeks

  • QuickDASH Score

    Upper limb function assessed using the Quick Disabilities of the Arm, Shoulder and Hand (QuickDASH) questionnaire.

    Baseline (pre-intervention) and 4 weeks

Study Arms (2)

Myofascial Release

EXPERIMENTAL

Participants received myofascial release techniques combined with conventional rehabilitation following flexor tendon repair.

Other: Myofascial Release

Hand Mobilization

EXPERIMENTAL

Participants received hand mobilization techniques combined with conventional rehabilitation following flexor tendon repair.

Other: Hand Mobilization

Interventions

Myofascial ReleaseOTHER

Myofascial release is a manual therapy technique applied after flexor tendon repair as part of the rehabilitation program. The technique aims to improve soft tissue mobility, reduce myofascial restrictions, enhance wrist and hand range of motion, and improve functional outcomes.

Myofascial Release
Hand MobilizationOTHER

Hand mobilization is a rehabilitation technique applied after flexor tendon repair to improve tendon gliding, wrist and hand range of motion, and functional recovery.

Hand Mobilization

Eligibility Criteria

Age20 Years - 45 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • The subject selection will be based on the following criteria:
  • years of age
  • Post-flexor tendon repair surgery in zone 2 within 2-4 weeks
  • Ability to understand and follow study instructions
  • Willingness to participate in the rehabilitation program

You may not qualify if:

  • Potential participants will be excluded if they meet one of the following criteria:
  • Severe joint deformities or arthritis in the wrist or hand
  • Infections or other complications related to the tendon repair
  • History of neurological disorders or conditions affecting hand function
  • Non-compliance or contraindications to manual therapy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Physical Therapy, Cairo University

Giza, Giza Governorate, Egypt

Location

MeSH Terms

Interventions

Myofascial Release Therapy

Intervention Hierarchy (Ancestors)

MassageTherapy, Soft TissueMusculoskeletal ManipulationsComplementary TherapiesTherapeuticsPhysical Therapy ModalitiesRehabilitation

Study Officials

  • Hussin Gamal Megahed, Professor

    Research Ethical Committee Faculty of Physical Therapy Cairo University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Participants will be randomly assigned to one of two parallel intervention groups. One group will receive hand mobilization with conventional rehabilitation, while the other group will receive myofascial release with conventional rehabilitation.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Physiotherapist at ministry of health

Study Record Dates

First Submitted

July 8, 2026

First Posted

July 16, 2026

Study Start

April 1, 2026

Primary Completion

July 1, 2026

Study Completion

July 2, 2026

Last Updated

July 16, 2026

Record last verified: 2026-07

Data Sharing

IPD Sharing
Will not share

Locations

EG(1)