The Effect of Osteopathic Visceral Manipulation on Pain, Mobility and Functional Disability in Patients With Right Shoulder Adhesive Capsulitis

NCT07704411 | Completed

• 1 other identifier: 2022/0670
• Study Type: interventional
• Target: 56
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study was to evaluate the effects of adding osteopathic visceral manipulation (OVM) to a standard physical therapy program on pain, functional disability, and range of motion (ROM) in patients diagnosed with right shoulder adhesive capsulitis (AC). A total of 49 patients aged between 40 and 65 years who were diagnosed with right shoulder AC were included in the study. Randomized patients received a standard physical therapy program for three weeks, consisting of 15 sessions (5 days per week) in both treatment groups. The standard program included hot pack application to the shoulder region for 20 min, conventional transcutaneous electrical nerve stimulation (TENS) for 20 min, and ultrasound therapy at 1.5 W/cm² for 10 min. In addition to the standard physical therapy program, Group 1 (n=25) received OVM once weekly, while Group 2 (n=24) received sham OVM once weekly. Pain was evaluated using the Visual Analog Scale (VAS), while functional disability was evaluated using the Shoulder Pain and Disability Index (SPDI). The ROM values were also recorded.

Conditions

Shoulder Adhesive Capsulitis; Osteopathic Manipulative Treatment (OMT)

Keywords

Adhesive capsulitis; osteopathic visceral manipulation; physical therapy; visceral dysfunction

Outcome Measures

Primary Outcomes (1)

• Pain (VAS)

  From enrollment to the end of treatment at 4 weeks

Secondary Outcomes (2)

• Active shoulder ROM for abduction, flexion, internal rotation, and external rotation

  From enrollment to the end of treatment at 4 weeks

• Shoulder Pain and Disability Index (SPADI)

  From enrollment to the end of treatment at 4 weeks

Study Arms (2)

Group 1 (OVM group, n=28) received a standard physical therapy program

EXPERIMENTAL

Other: physical therapy program

Group 2 (Sham group, n=28) received the same standard physical therapy program

SHAM COMPARATOR

Other: Sham (No Treatment)

Interventions

physical therapy program OTHER

In the OVM group, mobilization of the liver and diaphragm was performed. Liver mobilization was applied in three planes (coronal, transverse, and sagittal) for 5 min each, totaling 15 min, while the diaphragm technique was applied for 2 min.

Group 1 (OVM group, n=28) received a standard physical therapy program

Sham (No Treatment) OTHER

In the sham OVM group, light pressure and touch were applied with the palm over the same points selected for OVM, without the intention of providing therapeutic effect.

Group 2 (Sham group, n=28) received the same standard physical therapy program

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age between 18 and 65 years
• Presence of pain originating from the right shoulder region persisting for at least 6 weeks
• Availability of two-view shoulder radiographs obtained prior to the study to exclude causes of shoulder pain other than AC
• No local corticosteroid injection for shoulder pain within the previous 6 months
• No physical therapy administered for shoulder pain within the previous 6 months
• No use of non-steroidal anti-inflammatory drugs (NSAIDs) during the study period
• Availability of laboratory assessments including:
• Complete blood count (CBC)
• Erythrocyte sedimentation rate (ESR)
• Liver function tests (AST, ALT)
• C-reactive protein (CRP)
• Pain intensity score of at least 4 cm on the Visual Analog Scale (VAS, 0-10 cm)

You may not qualify if:

• History of shoulder fracture on the affected side
• Prior shoulder surgery
• History of traumatic shoulder instability (subluxation or dislocation)
• History of shoulder or visceral organ surgery within the past 6 months
• History of systemic or inflammatory disease or malignancy
• Presence of metabolic or endocrine bone disease
• Pregnancy
• Neurological disorders affecting upper extremity function
• Psychiatric disorders that could interfere with treatment compliance or symptom evaluation
• Use of antiplatelet medication
• Previous osteopathic treatment

Sponsors & Collaborators

• Istanbul Medeniyet University: lead

Study Sites (1)

Goztepe Suleyman Yalcin Sehir Hastanesi Fiziksel Tıp ve Rehabilitasyon Klinigi

Istanbul, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Bursitis

Interventions

salicylhydroxamic acid

Condition Hierarchy (Ancestors)

Joint Diseases; Musculoskeletal Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Model Details: Single-center, single-blind, randomized-controlled study

Study Record Dates

• First Submitted: July 6, 2026
• First Posted: July 15, 2026
• Study Start: January 10, 2023
• Primary Completion: May 15, 2024
• Study Completion: March 20, 2025
• Last Updated: July 15, 2026

Record last verified: 2026-07

Locations

TU (1)