Tai-Chi Exercise Reduces Fatigue in Breast Cancer Patients Undergoing Chemotherapy

NCT07702409 | Completed

• 1 other identifier: 077/KEPK/II
• Study Type: interventional
• Target: 61
• Locations: 1 country
• Sites: 1

Brief Summary

Tai-Chi Exercise Reduces Fatigue in Breast Cancer Patients Undergoing Chemotherapy. The main question it aims to answer is: Does Tai-chi training reduce fatigue in breast cancer patients? Participants performed the exercise on the day agreed upon with the researcher. All participants were given routine care, and leaflets related to chemotherapy, psychological aspects of cancer patients, nutrition, and management of cancer symptoms. While respondents in the intervention group received 5 times Tai-Chi practice interventions in a week for 3 weeks with a duration of 30 minutes of each practice, using 18 forms of Tai-Chi shibashi adapted from Yang's style. Before the Tai-Chi intervention is implemented, standard training was given once to each respondent by an experienced Tai-Chi master, as well as video tutorials for independent practice at home demonstrated by the Tai-Chi master. During the three weeks of practicing Tai-Chi at home, each respondent was asked to fill out a logbook for each exercise, and fill out a fatigue questionnaire every three days, while the control group was asked to fill out their daily physical activities reports on the logbook. The researcher invited the intervention group respondents to the WhatsApp Group to remind the participants to practice the Tai-Chi exercise at home every day, evaluate side effects during exercise and fill out a fatigue questionnaire in the logbook. The researcher also invited control group respondents to the WhatsApp Group to remind participants to fill in their daily physical activities and fill out fatigue questionnaires in the logbook. Research respondents who met the inclusion criteria were randomized by research assistants using block randomization with sorted random tables, the order of randomization was kept by research assistants who were not directly involved in the study. After the respondents who met the requirements were identified and completed the pre-test, the researcher contacted the research assistant to place the respondents in the intervention or control group according to a pre-determined randomization sequence. Due to the observable nature of Tai-Chi practice, the lack of a sham comparison group, and the pre-test and post-test measurements reported by the respondents, blindness could not be performed on the respondents. Data collection and follow-up is carried out every 3 days via chat or telephone. Based on the initial sample count, there were 23 respondents in each group (n = 46), and to cover the possibility of 25% drop-out respondents, the correction for the sample size of this study was 61 respondents, 31 respondents in the intervention group, 30 respondents in the control.

Conditions

Breast Cancer; Breast Cancer and Rehabilitation

Keywords

Breast Cancer; Breast Cancer and rehabilitation; Tai-Chi Exercise; Reduces Fatigue; Chemotherapy

Outcome Measures

Primary Outcomes (1)

• Reduced Fatigue

  Reduced Fatigue Scores

  3 Weeks

Study Arms (2)

Intervention Group

EXPERIMENTAL

Performed Tai-Chi

Behavioral: Tai-chi

Control Group

EXPERIMENTAL

Performed Daily Physical Activities

Behavioral: Daily Physical Activities

Interventions

Tai-chi BEHAVIORAL

All participants were given routine care, and leaflets related to chemotherapy, psychological aspects of cancer patients, nutrition, and management of cancer symptoms. While respondents in the intervention group received 5 times Tai-Chi practice interventions in a week for 3 weeks with a duration of 30 minutes of each practice, using 18 forms of Tai-Chi shibashi adapted from Yang's style. Before the Tai-Chi intervention is implemented, standard training was given once to each respondent by an experienced Tai-Chi master, as well as video tutorials for independent practice at home demonstrated by the Tai-Chi master. During the three weeks of practicing Tai-Chi at home, each respondent was asked to fill out a logbook for each exercise, and fill out a fatigue questionnaire every three days. The researcher invited the intervention group respondents to the WhatsApp Group to remind the participants to practice the Tai-Chi exercise at home every day, evaluate side effects during exercise.

Intervention Group

Daily Physical Activities BEHAVIORAL

All participants were given routine care, and leaflets related to chemotherapy, psychological aspects of cancer patients, nutrition, and management of cancer symptoms. While the control group was asked to fill out their daily physical activities reports on the logbook. The researcher also invited control group respondents to the WhatsApp Group to remind participants to fill in their daily physical activities and fill out fatigue questionnaires in the logbook.

Control Group

Eligibility Criteria

• Age: 18 Years - 64 Years
• Gender Eligibility Details: Female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

Sponsors & Collaborators

• Chairul Huda: lead

Study Sites (1)

Dharmais Cancer Hospital

Jakarta, Jakarta Special Capital Region, 11420, Indonesia

Location

MeSH Terms

Conditions

Breast Neoplasms

Interventions

Tai Ji

Condition Hierarchy (Ancestors)

Neoplasms by Site; Neoplasms; Breast Diseases; Skin Diseases; Skin and Connective Tissue Diseases

Intervention Hierarchy (Ancestors)

Mind-Body Therapies; Complementary Therapies; Therapeutics; Exercise Movement Techniques; Physical Therapy Modalities

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: Outcome assessors were not involved during the intervention process. Respondents were also asked not to inform the outcome assessor of the measures they received.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Ns. Chairul Huda, S.Kep., M.Kep., Sp.Kep.M.B

Model Details: This study used a parallel Randomized Controlled Trial (RCT) with a 1:1 ratio

Study Record Dates

• First Submitted: July 9, 2026
• First Posted: July 14, 2026
• Study Start: March 20, 2026
• Primary Completion: May 28, 2026
• Study Completion: June 15, 2026
• Last Updated: July 14, 2026

Record last verified: 2026-07

Data Sharing

• IPD Sharing: Will not share

Locations

ID (1)