NCT07701226

Brief Summary

This study evaluated a novel tracheostomy tube fixation device in post-tracheostomy patients with oral cancer. After tracheostomy, conventional fixation methods may be associated with skin pressure injury, wound contamination, frequent dressing changes, tube displacement, and patient discomfort. The novel fixation device was designed to provide stable tube fixation, protect the cervical skin, facilitate wound care, and improve patient comfort. A total of 150 eligible patients who underwent tracheostomy were randomly assigned to a treatment group or a control group. Patients in the control group received routine tracheostomy care and conventional fixation. Patients in the treatment group received the novel self-adhesive bidirectional tracheostomy tube fixation device in addition to routine tracheostomy care. The study assessed whether the novel fixation device could reduce tracheostomy-related complications, improve nursing efficiency, reduce the frequency and duration of wound care, improve neck comfort, and maintain safe tracheostomy tube fixation.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
150

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started May 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 7, 2025

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 31, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 31, 2025

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

July 9, 2026

Completed
5 days until next milestone

First Posted

Study publicly available on registry

July 14, 2026

Completed
Last Updated

July 14, 2026

Status Verified

July 1, 2026

Enrollment Period

6 months

First QC Date

July 9, 2026

Last Update Submit

July 9, 2026

Conditions

Keywords

Novel Tracheostomy Tube Fixation DeviceTracheostomy Tube FixationTracheostomy CareAirway RehabilitationNursing EfficiencyComplication RatePatient ComfortTracheostomy Wound CareCervical Skin InjuryTube DisplacementOral Cancer PatientsRandomized Controlled Trial

Outcome Measures

Primary Outcomes (1)

  • Incidence of Tracheostomy Wound Infection

    The occurrence of infection or inflammatory signs around the tracheostomy wound was assessed, including redness, swelling, heat, and pain around the tracheostomy site.

    From intervention initiation to hospital discharge, up to 14 days

Secondary Outcomes (5)

  • Frequency of Dressing or Device Replacement

    From intervention initiation to hospital discharge, up to 14 days

  • Duration of Each Dressing or Device Replacement Procedure

    From intervention initiation to hospital discharge, up to 14 days

  • Incidence of New Cervical Skin Injury

    From postoperative day 1 to hospital discharge, up to 14 days

  • Incidence of Tracheostomy Tube Displacement

    From intervention initiation to hospital discharge, up to 14 days

  • Patient-Reported Neck Comfort Score

    From intervention initiation to hospital discharge, up to 14 days

Other Outcomes (2)

  • Change in Oxygen Saturation Before and After Device Use

    Before and after device or dressing use during hospitalization, up to 14 days

  • Incidence of Adverse Events

    From intervention initiation to hospital discharge, up to 14 days

Study Arms (2)

Treatment Group

EXPERIMENTAL

Participants in the treatment group received routine tracheostomy care plus a novel self-adhesive bidirectional tracheostomy tube fixation device. The device was applied for tracheostomy tube fixation and was replaced once daily, or earlier if blood or exudate soaked two-thirds of the device.

Device: Novel Self-Adhesive Bidirectional Tracheostomy Tube Fixation DeviceOther: Routine Tracheostomy Care and Conventional Fixation

Control Group

ACTIVE COMPARATOR

Participants in the control group received routine tracheostomy care and conventional tracheostomy tube fixation. Routine care included nebulization therapy as prescribed, sputum suctioning as needed, regular cleaning or replacement of the inner cannula, and sterile gauze dressing care.

Other: Routine Tracheostomy Care and Conventional Fixation

Interventions

The novel self-adhesive bidirectional tracheostomy tube fixation device was used for tracheostomy tube fixation in addition to routine tracheostomy care. After drying the wound area, the device was placed between the patient and the tracheostomy tube, with the posterior side attached to the cervical skin. The anterior hook-and-loop components were passed through the fixation wings of the tracheostomy tube and adjusted to secure the tube. The device was replaced once daily, or earlier if blood or exudate soaked two-thirds of the device.

Treatment Group

Routine tracheostomy care included conventional tracheostomy tube fixation, nebulization therapy as prescribed, sputum suctioning as needed, regular cleaning or replacement of the inner cannula, and sterile gauze dressing care. Conventional fixation was performed using gauze ties or routine fixation straps around the neck with appropriate tightness. The tracheostomy wound dressing was changed twice daily or earlier if blood or exudate soaked two-thirds of the gauze dressing.

Control GroupTreatment Group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients aged 18 years or older.
  • Patients with oral cancer who underwent tracheostomy or required a tracheostomy tube during hospitalization.
  • Patients who were conscious and had normal comprehension and communication ability.
  • Patients with intact cervical skin without skin damage, skin disease, or infection.
  • Patients who voluntarily agreed to participate and provided written informed consent.

You may not qualify if:

  • Patients with pre-existing pressure injury, skin damage, allergy, or infection in the anterior cervical region before tracheostomy.
  • Pregnant women.
  • Minors under 18 years of age.
  • Patients with psychiatric disorders.
  • Patients who were unable to cooperate with the study procedures or outcome assessments as judged by the investigators.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine

Shanghai, Shanghai Municipality, 200011, China

Location

MeSH Terms

Conditions

Mouth Neoplasms

Condition Hierarchy (Ancestors)

Head and Neck NeoplasmsNeoplasms by SiteNeoplasmsMouth DiseasesStomatognathic Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Masking Details
This was an open-label study because the tracheostomy tube fixation method was visible to both participants and care providers. No masking was implemented.
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Model Details: This is a two-arm, parallel, randomized controlled trial. Eligible post-tracheostomy patients were randomly assigned to either the treatment group or the control group. The control group received routine tracheostomy care and conventional fixation, while the treatment group received routine tracheostomy care plus a novel self-adhesive bidirectional tracheostomy tube fixation device.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

July 9, 2026

First Posted

July 14, 2026

Study Start

May 7, 2025

Primary Completion

October 31, 2025

Study Completion

October 31, 2025

Last Updated

July 14, 2026

Record last verified: 2026-07

Data Sharing

IPD Sharing
Will share

De-identified individual participant data underlying the main study results will be shared after removal of personal identifiers. Shared data may include baseline characteristics, intervention records, outcome measures, and adverse event data. No names, hospital identification numbers, contact information, or other personally identifiable information will be shared.

Shared Documents
STUDY PROTOCOL, SAP, ICF
Time Frame
Beginning November 1, 2026, and available for 5 years.
Access Criteria
Data will be available to qualified researchers for academic and non-commercial research purposes after submission of a reasonable request and approval by the principal investigator and the study institution. Requesters will be required to sign a data use agreement and comply with ethical and privacy protection requirements.

Locations