NCT07699458

Brief Summary

the goal of this clinical trial is to study the Impact of adding integrated neuromuscular inhibition technique to cervical stabilization exercise in chronic mechanical neck pain

Trial Health

63
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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
63

participants targeted

Target at P50-P75 for not_applicable

Timeline
5mo left

Started Aug 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 20, 2026

Completed
2 months until next milestone

First Posted

Study publicly available on registry

July 13, 2026

Completed
1 month until next milestone

Study Start

First participant enrolled

August 25, 2026

Expected
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 10, 2026

2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

January 25, 2027

Last Updated

July 13, 2026

Status Verified

July 1, 2026

Enrollment Period

4 months

First QC Date

May 20, 2026

Last Update Submit

July 7, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Pain threshold

    Measured by using Pressure algometer

    One month

Secondary Outcomes (4)

  • pain intensity

    One month

  • Range of Motion

    One month

  • Neck function

    One month

  • Neck proprioception

    One month

Study Arms (3)

cervical stabilization exercise plus integrated neuromuscular inhibition technique

EXPERIMENTAL

this group will recive cervical stablization exercise whice starting with cervical isometric exercises performed in the supine position. The head will be supported on a pillow with a towel roll placed under the cervical spine to ensure proper alignment. Additional cervical isometric exercises will be conducted in the seated position by applying manual resistance at the forehead to perform cervical flexion, extension, rotation, and side-bending movements. and integrated Neuromuscular Inhibition be applied to the upper trapezius muscle to deactivate myofascial trigger points and reduce muscle tension. The technique will consist of three sequential components: intermittent ischemic compression, strain counterstain, and muscle energy technique.and conventional physical therapy(superficial heat using hot pack for 10 minutes, stretching exercise, isometric neck exercise and posture advice)

Device: Cervical stabilization exercise and Integrated Neuromuscular Inhibition

integrated neuromuscular inhibition technique

EXPERIMENTAL

this group integrated Neuromuscular Inhibition be applied to the upper trapezius muscle to deactivate myofascial trigger points and reduce muscle tension. The technique will consist of three sequential components: intermittent ischemic compression, strain counterstain, and muscle energy technique.and conventional physical therapy(superficial heat using hot pack for 10 minutes, stretching exercise, isometric neck exercise and posture advice)

Device: Integrated neuromuscular inhibition technique

conventional treatment

ACTIVE COMPARATOR

Participants in this group will receive conventional physical therapy only in the form of: (superficial heat using hot pack for 10 minutes, stretching exercise, isometric neck exercise and posture advice) for 3 sessions/week over 4 weeks' periods.

Other: Conventional Treatment group

Interventions

cervical stablization exercise starting with cervical isometric exercises performed in the supine position. The head will be supported on a pillow with a towel roll placed under the cervical spine to ensure proper alignment. Additional cervical isometric exercises will be conducted in the seated position by applying manual resistance at the forehead to perform cervical flexion, extension, rotation, and side-bending movements. The Integrated Neuromuscular Inhibition will be applied to the upper trapezius muscle to deactivate myofascial trigger points and reduce muscle tension. The technique will consist of three sequential components: intermittent ischemic compression, strain counterstain, and muscle energy technique

cervical stabilization exercise plus integrated neuromuscular inhibition technique

Integrated Neuromuscular Inhibition will be applied to the upper trapezius muscle to deactivate myofascial trigger points and reduce muscle tension. The technique will consist of three sequential components: intermittent ischemic compression, strain counterstain, and muscle energy technique

integrated neuromuscular inhibition technique

Participants in this group will receive conventional physical therapy only in the form of superficial heat using hot pack for 10 minutes, stretching exercise, isometric neck exercise and posture advice for 3 sessions/week over 4 weeks' periods.

conventional treatment

Eligibility Criteria

Age18 Years - 44 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Age from 18-44 year
  • Their body mass index will be ranging from (18-25) Kg/m2
  • All patient has active cervical trigger point of the upper fiber of the Trapezius detected by pincer palpation
  • Subjects must have characteristics of trigger points hardened, thickened taut bands in MPS patients.

You may not qualify if:

  • Individuals with a recent history of neck or back surgery.
  • Individuals with recent history of trauma or fracture.
  • Individuals with congenital and pathological disorders of the cervical spine.
  • Individuals with any psychiatric diseases

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Fuclty of Physical Therapy

Cairo, Egypt

Location

Study Officials

  • Hytham mohammed elhafez, PhD

    Cairo University

    STUDY CHAIR
  • rania reda mohammed, PhD

    Cairo univeristy

    STUDY DIRECTOR
  • heba ahmed elgyar, PhD

    Cairo University

    STUDY DIRECTOR

Central Study Contacts

huda adel mohammed, assistant lecturer

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
assistant lecturer

Study Record Dates

First Submitted

May 20, 2026

First Posted

July 13, 2026

Study Start (Estimated)

August 25, 2026

Primary Completion (Estimated)

December 10, 2026

Study Completion (Estimated)

January 25, 2027

Last Updated

July 13, 2026

Record last verified: 2026-07

Locations