NCT07699198

Brief Summary

The purpose of this activity is to identify promising cannabis warning messages from different themes. Participants will be adults who live in the United States, including both people who use cannabis and those who do not use cannabis. In an online within-subjects experiment, participants will be randomly assigned to view 7 cannabis warning messages from different themes developed as part of previous study activities. After viewing each cannabis warning message, participants will rate the message on awareness, clarity, believability, cognitive elaboration, perceived message effectiveness, and reactance. The survey will take 15-20 minutes.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,500

participants targeted

Target at P75+ for not_applicable

Timeline
2mo left

Started Jul 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress59%
Jul 2026Nov 2026

First Submitted

Initial submission to the registry

June 25, 2026

Completed
18 days until next milestone

First Posted

Study publicly available on registry

July 13, 2026

Completed
Same day until next milestone

Study Start

First participant enrolled

July 13, 2026

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 30, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 30, 2026

Last Updated

July 13, 2026

Status Verified

June 1, 2026

Enrollment Period

5 months

First QC Date

June 25, 2026

Last Update Submit

July 8, 2026

Conditions

Keywords

CannabisMarijuana UseProduct PackagingProduct LabelingWarningsHealth Communication

Outcome Measures

Primary Outcomes (1)

  • Cognitive Elaboration

    A one item measure of cognitive elaboration to assess how much a message makes the participant think about the health risks of cannabis. Response options are on a 5-point scale from 5='A great deal' to 1= 'Not at all', with higher scores indicating higher cognitive elaboration.

    Baseline (one time online survey)

Secondary Outcomes (1)

  • Perceived Message Effectiveness

    Baseline (one time online survey)

Other Outcomes (3)

  • Clarity

    Baseline (one time online survey)

  • Believability

    Baseline (one time online survey)

  • Reactance

    Baseline (one time online survey)

Study Arms (1)

Cannabis warning messages

EXPERIMENTAL

Participants will view and rate 7 cannabis warning messages. The cannabis warning messages cover 11 different themes plus a control theme and were identified in a previous study activity. Theme 1: Constituents Theme 2: Cognitive Functioning Theme 3: Cardiovascular Health Theme 4: Motor Vehicle Crashes Theme 5: Dependence Theme 6: Psychosis and Schizophrenia Theme 7: Mental Health Theme 8: Reproductive Health Theme 9: Respiratory Health Theme 10: Edibles Theme 11: Cannabis Hyperemesis Syndrome Theme 12: Control

Behavioral: ConstituentsBehavioral: Cognitive FunctioningBehavioral: Cardiovascular HealthBehavioral: Motor Vehicle CrashesBehavioral: DependenceBehavioral: Psychosis and SchizophreniaBehavioral: Mental HealthBehavioral: Reproductive HealthBehavioral: Respiratory HealthBehavioral: EdiblesBehavioral: Cannabis Hyperemesis SyndromeBehavioral: Control

Interventions

ConstituentsBEHAVIORAL

Participants will view and rate a message about constituents.

Cannabis warning messages

Participants will view and rate a message about cognitive functioning.

Cannabis warning messages

Participants will view and rate a message about cardiovascular health.

Cannabis warning messages

Participants will view and rate a message about motor vehicle crashes.

Cannabis warning messages
DependenceBEHAVIORAL

Participants will view and rate a message about dependence.

Cannabis warning messages

Participants will view and rate a message about psychosis and schizophrenia.

Cannabis warning messages
Mental HealthBEHAVIORAL

Participants will view and rate a message about mental health.

Cannabis warning messages

Participants will view and rate a message about reproductive health.

Cannabis warning messages

Participants will view and rate a message about respiratory health.

Cannabis warning messages
EdiblesBEHAVIORAL

Participants will view and rate a message about edibles.

Cannabis warning messages

Participants will view and rate a message about cannabis hyperemesis syndrome.

Cannabis warning messages
ControlBEHAVIORAL

Participants will view and rate a control message.

Cannabis warning messages

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 18 years of age and older
  • Live in the United States

You may not qualify if:

  • Age less than 18 years of age
  • Does not live in the United States

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of North Carolina at Chapel Hill

Chapel Hill, North Carolina, 27514, United States

Location

MeSH Terms

Conditions

Marijuana AbuseMarijuana Use

Interventions

Functional StatusMental HealthReproductive Health

Condition Hierarchy (Ancestors)

Substance-Related DisordersChemically-Induced DisordersMental DisordersBehavior

Intervention Hierarchy (Ancestors)

Activities of Daily LivingRehabilitationHealth ServicesHealth Care Facilities Workforce and ServicesHealth StatusDemographyEpidemiologic MeasurementsPublic HealthEnvironment and Public HealthHealthPopulation Characteristics

Study Officials

  • Sarah D Kowitt, PhD, MPH

    University of North Carolina, Chapel Hill

    PRINCIPAL INVESTIGATOR
  • Leah M Ranney, PhD, MA

    University of North Carolina, Chapel Hill

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Sarah D Kowitt, PhD, MPH

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
PREVENTION
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 25, 2026

First Posted

July 13, 2026

Study Start

July 13, 2026

Primary Completion (Estimated)

November 30, 2026

Study Completion (Estimated)

November 30, 2026

Last Updated

July 13, 2026

Record last verified: 2026-06

Data Sharing

IPD Sharing
Will share

A de-identified version of individual participant data will be shared through the UNC Dataverse

Shared Documents
STUDY PROTOCOL, SAP
Time Frame
The dataset will be available after data collection and analysis and will remain available for 10 years
Access Criteria
Open Access

Locations