Prevalence of Functional Dyspepsia in a Rural Community of Bangladesh : A Cross Sectional Study

NCT07694778 | Recruiting DMC

• 1 other identifier: 5877
• Study Type: observational
• Target: 730
• Locations: 1 country
• Sites: 1

Brief Summary

Functional dyspepsia (FD) is a common gastrointestinal disorder with an important impact on quality of life. There is a paucity of updated data on the prevalence of FD in rural areas of Bangladesh. The present study will be carried out to find the prevalence of FD in a community in rural Bangladesh. It also assesses potential risk factors. Eligible participants will first be evaluated for symptoms by a clinical interview using the standardized Rome IV functional dyspepsia questionnaire. Those who meet Rome IV criteria will then have an upper gastrointestinal endoscopy to exclude underlying organic diseases to establish a definitive diagnosis. Eventually patients with normal endoscopic findings will be diagnosed as having functional dyspepsia. This allows the accurate calculation of disease prevalence. Researchers will gather demographic information, lifestyle habits, and dietary patterns. The results will give important baseline data on rural FD burdens. Such data can inform community health care interventions.

Conditions

Functional Dyspepsia

Outcome Measures

Primary Outcomes (1)

• Prevalence of Functional Dyspepsia in a Rural Community of Bangladesh

  From January 2026 to December 2026

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Place of study: Shimulia Union, Ashulia, Savar, Dhaka, Bangladesh. Study Population: All adults of two villages of Shimulia Union who will give their consent to participate in the study.

You may qualify if:

• Age 18 years or above
• Resident of the selected community

You may not qualify if:

• Known diagnosis of organic GI diseases.(e.g., Peptic ulcer disease, Inflammatory Bowel Disease, celiac disease, Malignancy, Intestinal Tuberculosis)
• Severe cognitive impairment, or critical illness
• Individuals with a history of major abdominal surgery
• Pregnant women

Sponsors & Collaborators

• Bangladesh Medical University: lead

Study Sites (1)

Bangladesh Medical University, Dhaka

Dhaka, Bangladesh

RECRUITING

Related Publications (10)

• Yamamoto Y, Furukawa S, Watanabe J, Kato A, Kusumoto K, Takeshita E, Ikeda Y, Yamamoto N, Kohara K, Saeki Y, Hiasa Y. Association Between Body Mass Index and Functional Dyspepsia in Young Japanese People. J Neurogastroenterol Motil. 2022 Apr 30;28(2):276-282. doi: 10.5056/jnm21076.

  PMID: 35362453 BACKGROUND

• Rahman MM, Ghoshal UC, Kibria MG, Sultana N, Yusuf MA, Nahar S, Ahmed F, Rowshon A, Hasan M. Functional Dyspepsia, Peptic Ulcer, and Helicobacter pylori Infection in a Rural Community of South Asia: An Endoscopy-Assisted Household Survey. Clin Transl Gastroenterol. 2021 Apr 16;12(4):e00334. doi: 10.14309/ctg.0000000000000334.

  PMID: 33878048 BACKGROUND

• Perveen I, Rahman MM, Saha M, Rahman MM, Hasan MQ. Prevalence of irritable bowel syndrome and functional dyspepsia, overlapping symptoms, and associated factors in a general population of Bangladesh. Indian J Gastroenterol. 2014 May;33(3):265-73. doi: 10.1007/s12664-014-0447-1. Epub 2014 Mar 26.

  PMID: 24664445 BACKGROUND

• Mounsey A, Barzin A, Rietz A. Functional Dyspepsia: Evaluation and Management. Am Fam Physician. 2020 Jan 15;101(2):84-88.

  PMID: 31939638 BACKGROUND

• Miwa H, Nagahara A, Asakawa A, Arai M, Oshima T, Kasugai K, Kamada K, Suzuki H, Tanaka F, Tominaga K, Futagami S, Hojo M, Mihara H, Higuchi K, Kusano M, Arisawa T, Kato M, Joh T, Mochida S, Enomoto N, Shimosegawa T, Koike K. Evidence-based clinical practice guidelines for functional dyspepsia 2021. J Gastroenterol. 2022 Feb;57(2):47-61. doi: 10.1007/s00535-021-01843-7. Epub 2022 Jan 21.

  PMID: 35061057 BACKGROUND

• Kovacs DB, Szekely A, Hubai AG, Palsson O. Prevalence, epidemiology and associated healthcare burden of Rome IV irritable bowel syndrome and functional dyspepsia in the adult population of Gibraltar. BMJ Open Gastroenterol. 2022 Aug;9(1):e000979. doi: 10.1136/bmjgast-2022-000979.

  PMID: 35953148 BACKGROUND

• Kim YS, Kim N. Functional Dyspepsia: A Narrative Review With a Focus on Sex-Gender Differences. J Neurogastroenterol Motil. 2020 Jul 30;26(3):322-334. doi: 10.5056/jnm20026.

  PMID: 32606255 BACKGROUND

• Harer KN, Hasler WL. Functional Dyspepsia: A Review of the Symptoms, Evaluation, and Treatment Options. Gastroenterol Hepatol (N Y). 2020 Feb;16(2):66-74.

  PMID: 34035704 BACKGROUND

• Esterita T, Dewi S, Suryatenggara FG, Glenardi G. Association of Functional Dyspepsia with Depression and Anxiety: A Systematic Review. J Gastrointestin Liver Dis. 2021 Jun 18;30(2):259-266. doi: 10.15403/jgld-3325.

  PMID: 33951117 BACKGROUND

• Abdelazim O, Hassnine AA, Fathy B, Mgdy A, Semeda N, Mahmoud SR, Saad ZM, Mahmoud HA. The prevalence of functional dyspepsia using Rome IV questionnaire among chronic kidney disease patients. Ren Fail. 2024 Dec;46(1):2344651. doi: 10.1080/0886022X.2024.2344651. Epub 2024 Apr 24.

  PMID: 38655865 BACKGROUND

Study Officials

• Mohammad Asadur Rahman

  Bangladesh Medical University

  STUDY DIRECTOR

Central Study Contacts

Jabadur Rahman Peom

CONTACT

+8801925311811; peom1994@gmail.com

Samia Khanam Yeana

CONTACT

+880 1671122573; khansamiayeana@gmail.com

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Phase B Resident

Study Record Dates

• First Submitted: July 5, 2026
• First Posted: July 10, 2026
• Study Start: January 10, 2026
• Primary Completion (Estimated): December 1, 2026
• Study Completion (Estimated): December 1, 2026
• Last Updated: July 10, 2026

Record last verified: 2026-07

Locations

BA (1)