Effects of the DASH Diet and Lifestyle Modification on Blood Pressure in Adults With Prehypertension

NCT07692971 | Completed

• 2 other identifiers: 2026.07.03.HLEEthics Committee
• Study Type: interventional
• Target: 32
• Locations: 0 countries
• Sites: N/A

Brief Summary

This pilot randomized controlled trial evaluated the effects of the Dietary Approaches to Stop Hypertension (DASH) diet and lifestyle modification on blood pressure in adults with prehypertension. The study was conducted among adults aged 20-64 years who were diagnosed with prehypertension based on one-week blood pressure monitoring. A total of 32 participants were randomly assigned to one of three groups: verbal lifestyle modification advice, DASH diet, or DASH diet combined with lifestyle modification. Participants were followed for 2 months. Blood pressure measurements were repeated at the end of the first and second months. Dietary intake, anthropometric measurements, body composition, physical activity records, and routine biochemical parameters were also assessed during the study.

Conditions

Prehypertension; Prehypertension (Elevated Blood Pressure) or Hypertension

Keywords

Prehypertension; DASH eating plan; life style modifications

Outcome Measures

Primary Outcomes (2)

• Change From Baseline in Systolic Blood Pressure at 2 Months

  Systolic blood pressure was measured in a seated position after a 5-minute rest. The outcome was defined as the change in systolic blood pressure from baseline to the end of the 2-month follow-up period.

  Baseline and Month 2

• Change From Baseline in Diastolic Blood Pressure at 2 Months

  Diastolic blood pressure was measured in a seated position after a 5-minute rest. The outcome was defined as the change in diastolic blood pressure from baseline to the end of the 2-month follow-up period.

  Baseline and Month 2

Secondary Outcomes (1)

• Change From Baseline in Body Weight at 2 Months

  Baseline and Month 2

Study Arms (3)

Lifestyle Modification Advice

ACTIVE COMPARATOR

Participants in this arm received verbal lifestyle modification advice, including reducing salt intake, avoiding salted foods, weight loss when body mass index was 25 kg/m² or higher, regular aerobic physical activity, and limiting alcohol consumption.

Behavioral: Lifestyle Modification Advice

DASH Diet

EXPERIMENTAL

Participants in this arm received an individualized Dietary Approaches to Stop Hypertension (DASH) diet plan. Total energy requirements were calculated, and dietary plans were prepared according to the recommended DASH food group servings.

Behavioral: DASH Diet

DASH Diet Plus Lifestyle Modification

EXPERIMENTAL

Participants in this arm received an individualized DASH diet plan combined with lifestyle modification recommendations. For participants with body mass index of 25 kg/m² or higher, energy requirements were calculated according to desirable body weight. Sodium intake was controlled according to DASH recommendations, and advice on weight management, physical activity, salt reduction, and alcohol limitation was provided.

Behavioral: Lifestyle Modification Advice; Behavioral: DASH Diet

Interventions

Lifestyle Modification Advice BEHAVIORAL

Participants received verbal lifestyle modification advice, including reducing salt intake, avoiding salted foods, weight loss or maintenance of normal body weight when appropriate, regular aerobic physical activity, and limiting alcohol consumption.

Also known as: Lifestyle Modification Advice DASH Diet Plus Lifestyle Modification

DASH Diet Plus Lifestyle Modification; Lifestyle Modification Advice

DASH Diet BEHAVIORAL

Participants received an individualized Dietary Approaches to Stop Hypertension (DASH) diet plan. Total energy requirements were calculated, and dietary plans were prepared according to the recommended DASH food group servings. In the DASH diet plus lifestyle modification arm, sodium intake was controlled by providing measured daily salt amounts according to DASH recommendations.

Also known as: DASH Diet DASH Diet Plus Lifestyle Modification

DASH Diet; DASH Diet Plus Lifestyle Modification

Eligibility Criteria

• Age: 20 Years - 64 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Adults aged 20 to 64 years
• Diagnosis of prehypertension based on one-week blood pressure monitoring
• Systolic blood pressure between 120 and 139 mmHg and/or diastolic blood pressure between 80 and 89 mmHg
• Willingness to participate in the study voluntarily
• Provision of written informed consent

You may not qualify if:

• Presence of kidney disease
• Pregnancy
• Lactation
• Diagnosis of cancer
• Use of vitamin or mineral supplements
• Performing more than 150 minutes of physical activity per week

Sponsors & Collaborators

• Antalya Bilim University: lead

MeSH Terms

Conditions

Prehypertension; Hypertension

Interventions

Dietary Approaches To Stop Hypertension

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases

Intervention Hierarchy (Ancestors)

Diet Therapy; Nutrition Therapy; Therapeutics; Diet; Nutritional Physiological Phenomena; Diet, Food, and Nutrition; Physiological Phenomena

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Masking Details: No masking was used. Participants and investigators were aware of the assigned intervention because the study involved dietary and lifestyle modification interventions.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Participants were randomly assigned to one of three parallel intervention groups: verbal lifestyle modification advice, DASH diet, or DASH diet combined with lifestyle modification. Each participant received only the intervention assigned to their group and was followed for 2 months.

Study Record Dates

• First Submitted: July 3, 2026
• First Posted: July 9, 2026
• Study Start: April 1, 2015
• Primary Completion: June 1, 2015
• Study Completion: June 1, 2015
• Last Updated: July 9, 2026

Record last verified: 2026-07

Data Sharing

• IPD Sharing: Will not share