VIA Versus Colposcopy

NCT07692919 | Not Yet Recruiting

• 1 other identifier: Soh-Med-26-6-23MS
• Study Type: observational
• Target: 200
• Locations: 0 countries
• Sites: N/A

Brief Summary

The aim of this study is to compare the effectiveness of visual inspection with acetic acid (VIA) versus colposcopy in terms of sensitivity and specificity in diagnosis of pre-malignant cervical lesions among women, and to assess the awareness of women regarding cervical cancer screening methods.

Conditions

Cervical Intraepithelial Neoplasia (CIN); Cervicitis

Keywords

CIN

Outcome Measures

Primary Outcomes (2)

• VIA Versus Colposcopy in terms of in terms of sensitivity and specificity

  Patients will be observed for any immediate discomfort or minor complications such as spotting, mild cramping, or vaginal irritation following VIA, colposcopy, or biopsy. All patients will be advised on post-procedure care, including avoiding vaginal do

  2 weeks

• sensitivity and specificity in diagnosis of pre-malignant cervical lesions among women

  Patients will be observed for any immediate discomfort or minor complications such as spotting, mild cramping, or vaginal irritation following VIA, colposcopy, or biopsy. All patients will be advised on post-procedure care, including avoiding vaginal douching, sexual activity, or use of tampons for a few days, if a biopsy will be performed. Results of the VIA, colposcopy, and histopathology will be explained to the patients, and appropriate follow-up or referral will be arranged for those with CIN 2, CIN 3, or carcinoma. Patients will be instructed to report any unusual bleeding, pain, or discharge immediately to the clinic.

  From enrollment to the the result at 14 days

Interventions

VIA OTHER

A 5% acetic acid solution will be applied to the cervix, and after one minute, the cervix will be inspected under adequate light

Eligibility Criteria

• Age: 25 Years - 65 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

outpatient clinic pateints

You may qualify if:

• Age from 25 to 65 years.
• Patient undergoing cervical cancer screening using VIA and colposcopy.
• Women with symptoms such as white discharge, post-coital bleeding, and intermenstrual bleeding.
• Women with the clinically unhealthy cervix (erosion, bleeding on touch, simple leukoplakia, keratinization)
• Women with Pap smear showing dysplasia.

You may not qualify if:

• Pregnant women (if VIA or colposcopy is contraindicated).
• Women with obvious invasive cervical cancer diagnosed previously.
• Women who refuse to provide informed consent or are unable to cooperate with the examination.
• Women having active vaginal bleeding.
• Any past treatment for cervical lesions.

Sponsors & Collaborators

• Sohag University: lead

MeSH Terms

Conditions

Uterine Cervical Dysplasia; Uterine Cervicitis

Condition Hierarchy (Ancestors)

Precancerous Conditions; Neoplasms; Uterine Cervical Diseases; Uterine Diseases; Genital Diseases, Female; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Genital Diseases

Central Study Contacts

bassam mahmoud abdallah Mahmoud Abdallah, resident

CONTACT

+201012200274; bmmcamille@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Bassam Mahmoud Abdallah Mahmoud

Study Record Dates

• First Submitted: July 3, 2026
• First Posted: July 9, 2026
• Study Start: August 1, 2026
• Primary Completion (Estimated): January 1, 2027
• Study Completion (Estimated): June 1, 2027
• Last Updated: July 9, 2026

Record last verified: 2026-07