Wearable Data for Personalized Prognostication in Cancer: A Registry Protocol

NCT07691008 | Not Yet Recruiting DMC

• 1 other identifier: 260059
• Study Type: observational
• Target: 1,200
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study receives physiological and lifestyle-related data from mobile phones to create an institutional database.

Conditions

Hematopoietic Neoplasm; Malignant Solid Neoplasm; Lymphatic System Neoplasm; Hematopoietic and Lymphatic System Neoplasm

Outcome Measures

Primary Outcomes (1)

• Feasibility of data collection

  The proportion of participants for whom a successful data connection is established between their Apple Health data and the study registry will be quantified". Then for each variable captured by Apple Health, we will quantify the following feasibility metrics for data collection, evaluated separately for the retrospective (up to 8 years) and prospective (up to 5 years) data periods: For each subject, the total amount of retrospective (and prospective) HealthKit data available per patient in days and months will be calculated. For each subject, the number of days per week that a variable is available will be estimated and summarized by the average and standard deviation across weeks (or months). For both 1-2, the metrics will be calculated when pooling all available data, and separately for windows of 6 months. We will examine histograms and boxplots of the distributions across the cohort.

  Up to 8.5 years

Study Arms (1)

Observational

Participants have health data collected from their mobile phone for up to 5 years throughout the study.

Other: Non-Interventional Study

Interventions

Non-Interventional Study OTHER

Non-Interventional Study

Also known as: Non-Interventional Observational Study, non-interventional study, Noninterventional (Observational) Study

Observational

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients and employees at City of Hope MedicalCenter that own an apple mobile device.

You may qualify if:

• Age: ≥ 18 years
• Has Apple Health app on personal device with valid iOS operating software (i.e., iOS 15.0 or higher)
• Has a registered MyChart/MyCityofHope account (or be willing to register for one) and the app downloaded onto the personal device that also contains the Apple Health app with their data
• Ability to read and understand English to review MyChart/MyCityofHope on-screen instructions to sync and share Apple Health data
• Meets one of the below criteria:
• Any patient at City of Hope who had and/or has a cancer-related visit (e.g., high risk, newly diagnosed, receiving treatment, active follow-up, survivorship etc.)
• City of Hope employee

You may not qualify if:

• Prospective participants who, in the opinion of the investigator, may not be able to comply with all study procedures (including compliance issues related to feasibility/logistics)
• City of Hope employees listed on the study roster or who manage employees listed on the study roster

Sponsors & Collaborators

• City of Hope Medical Center: lead

MeSH Terms

Conditions

Hematologic Neoplasms

Condition Hierarchy (Ancestors)

Neoplasms by Site; Neoplasms; Hematologic Diseases; Hemic and Lymphatic Diseases

Study Officials

• Lee Jones

  City of Hope Medical Center

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Lee Jones

CONTACT

626-761-2214; leejones@coh.org

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 1, 2026
• First Posted: July 8, 2026
• Study Start (Estimated): December 1, 2026
• Primary Completion (Estimated): December 1, 2028
• Study Completion (Estimated): December 1, 2034
• Last Updated: July 8, 2026

Record last verified: 2026-07