Modified PENG Plus Suprascapular Nerve Block Versus Interscalene Block for Bankart and Latarjet Surgery

NCT07689045 | Recruiting

• 1 other identifier: MD-248-2025
• Study Type: interventional
• Target: 70
• Locations: 1 country
• Sites: 1

Brief Summary

This randomized controlled trial aims to compare the analgesic efficacy and safety of a Modified Pericapsular Nerve Group (PENG) Block combined with Suprascapular Nerve Block (SSNB) versus Interscalene Brachial Plexus Block (ISB) in adult patients undergoing elective Bankart repair or Latarjet surgery under general anesthesia. Seventy patients will be randomized to receive either Modified PENG plus SSNB or ISB. The primary outcome is postoperative pain intensity measured by the Visual Analog Scale (VAS) at 24 hours. Secondary outcomes include opioid consumption, time to first rescue analgesia, functional recovery, range of motion, and block-related complications including respiratory compromise, motor weakness, Horner syndrome, hoarseness, and local anesthetic systemic toxicity. This randomized controlled trial aims to compare the analgesic efficacy and safety of a Modified Pericapsular Nerve Group (PENG) Block combined with Suprascapular Nerve Block (SSNB) versus Interscalene Brachial Plexus Block (ISB) in adult patients undergoing elective Bankart repair or Latarjet surgery under general anesthesia. Seventy patients will be randomized to receive either Modified PENG plus SSNB or ISB. The primary outcome is postoperative pain intensity measured by the Visual Analog Scale (VAS) at 24 hours. Secondary outcomes include opioid consumption, time to first rescue analgesia, functional recovery, range of motion, and block-related complications including respiratory compromise, motor weakness, Horner syndrome, hoarseness, and local anesthetic systemic toxicity.

Conditions

Shoulder Instability

Outcome Measures

Primary Outcomes (1)

• Visual Analog Scale (VAS) Pain Score at Rest at 24 Hours Postoperatively

  Pain intensity at rest will be assessed using the Visual Analog Scale (VAS) for pain, ranging from 0 (no pain) to 10 (worst imaginable pain), 24 hours after surgery. Higher scores indicate worse pain. The primary comparison is between the Modified PENG Block combined with Suprascapular Nerve Block and the Interscalene Brachial Plexus Block.

  24 hours after surgery

Secondary Outcomes (2)

• Visual Analog Scale (VAS) Pain Scores at Postoperative Time Points

  multiple postoperative time points.

• Total opioid consumption

  during the first 24 hours.

Study Arms (2)

Modified PENG + Suprascapular Nerve Block (SSNB)

EXPERIMENTAL

Participants receive an ultrasound-guided Modified Pericapsular Nerve Group (PENG) Block combined with Suprascapular Nerve Block (SSNB) before induction of general anesthesia for elective Bankart repair or Latarjet surgery. The Modified PENG Block is performed with 20 mL of 0.25% bupivacaine and the SSNB with 10 mL of 0.25% bupivacaine.

Procedure: • Modified PENG Block combined with Suprascapular Nerve Block

Interscalene Brachial Plexus Block (ISB)

ACTIVE COMPARATOR

Participants receive an ultrasound-guided Interscalene Brachial Plexus Block (ISB) using 20 mL of 0.25% bupivacaine before induction of general anesthesia for elective Bankart repair or Latarjet surgery

Procedure: • Interscalene Brachial Plexus Block

Interventions

• Modified PENG Block combined with Suprascapular Nerve Block PROCEDURE

Ultrasound-guided Modified Pericapsular Nerve Group (PENG) Block combined with Suprascapular Nerve Block (SSNB) performed before induction of general anesthesia. The Modified PENG Block is performed with 20 mL of 0.25% bupivacaine and the SSNB with 10 mL of 0.25% bupivacaine for postoperative analgesia in patients undergoing elective Bankart repair or Latarjet surgery

Modified PENG + Suprascapular Nerve Block (SSNB)

• Interscalene Brachial Plexus Block PROCEDURE

Ultrasound-guided Interscalene Brachial Plexus Block performed before induction of general anesthesia using 20 mL of 0.25% bupivacaine for postoperative analgesia in patients undergoing elective Bankart repair or Latarjet surgery

Interscalene Brachial Plexus Block (ISB)

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Male or female patients aged 18 to 65 years.
• Patients undergoing elective Bankart repair or Latarjet surgery.
• American Society of Anesthesiologists (ASA) physical status I or II.
• History of allergy to local anesthetics.
• Chronic opioid use (\>3 months).
• Coagulation disorders.
• Pre-existing neurological or musculoskeletal disorders.
• Respiratory compromise (e.g., COPD)

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Faculty of Medicine , Cairo University Hospitals

Cairo, Cairo Governorate, Egypt

RECRUITING

Study Officials

• Ahmed Zaghloul Foaad, Professor of Anaesthesia

  Cairo University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Ahmed Hamza Ibrahem Mohamed, MD

CONTACT

+201159518716; ahmedmedohamza@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Masking Details: Participants and outcome assessors will be blinded to treatment allocation. Randomization will be performed using computer-generated random numbers and sealed opaque envelopes. The anesthesiologist performing the block will not be blinded because of the nature of the intervention
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assistant lecture

Model Details: Participants will be randomly assigned in a 1:1 ratio to one of two parallel groups: Modified PENG Block combined with Suprascapular Nerve Block (SSNB) or Interscalene Brachial Plexus Block (ISB). Participants remain in their assigned group throughout the study.

Study Record Dates

• First Submitted: June 30, 2026
• First Posted: July 7, 2026
• Study Start: June 1, 2026
• Primary Completion (Estimated): November 1, 2026
• Study Completion (Estimated): November 29, 2026
• Last Updated: July 8, 2026

Record last verified: 2026-07

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)