NCT07688382

Brief Summary

  1. 1.To analyze the therapeutic effects of lavender aromatherapy on memory function and overall cognitive function in older adults with Mild Cognitive Impairment (MCI);
  2. 2.To analyze whether lavender aromatherapy improves executive function, language ability, attention, visuospatial ability, anxiety, depression, quality of life, and sleep in older adults with MCI.

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
70

participants targeted

Target at P50-P75 for not_applicable

Timeline
4mo left

Started Sep 2026

Shorter than P25 for not_applicable

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 2, 2026

Completed
5 days until next milestone

First Posted

Study publicly available on registry

July 7, 2026

Completed
2 months until next milestone

Study Start

First participant enrolled

September 1, 2026

Expected
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2027

1 day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 2, 2027

Last Updated

July 7, 2026

Status Verified

July 1, 2026

Enrollment Period

4 months

First QC Date

July 2, 2026

Last Update Submit

July 2, 2026

Conditions

MCI

Outcome Measures

Primary Outcomes (2)

  • Gobal cognitive function

    Use the Mini-Mental State Examination to assess overall cognitive function.

    Week 12

  • Memory

    Use the Auditory Verbal Learning Test to assess memory function.

    Week 12

Secondary Outcomes (8)

  • Language function

    Week 12

  • Executive function

    Week 12

  • Visual space

    Week 12

  • Attention

    Week 12

  • Anxiety

    Week 12

  • +3 more secondary outcomes

Study Arms (2)

Aromatherapy experimental group

OTHER

Aromatherapy experimental group : Aromatherapy The aromatherapy intervention protocol is as follows: Based on the elderly participant's usual bedtime, record the time they go to bed; instruct them to assume a comfortable sleeping position; using the graduated dropper provided with the essential oil bottle, dispense 0.15 ml (approximately 3 drops; theoretically, 0.05 ml per drop) of diluted lavender essential oil and drip it vertically onto the upper center of a cotton pad; pin the cotton pad to the collar with a safety pin; and have the participant inhale the scent evenly for 30 minutes. Afterward, the intervention staff or caregiver will remove the cotton pad. The intervention will be conducted 5 days a week for 12 weeks.

Other: aromatherapy

Control group

NO INTERVENTION

no-treatment control group receiving routine health education only

Interventions

aromatherapyOTHER

Participants in the intervention group will receive aromatherapy inhalation for 30 minutes per session, five times a week, over a period of 12 week

Aromatherapy experimental group

Eligibility Criteria

Age60 Years - 95 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • The MCI mentioned in this study meets the diagnostic criteria proposed by the \*Chinese Expert Consensus on the Diagnosis and Treatment of Alzheimer's Disease-Derived Mild Cognitive Impairment (2021)\*: cognitive impairment reported by the patient or an informant, or identified by an experienced clinician; objective evidence of impairment in one or more cognitive domains, with episodic memory impairment being the most common; complex instrumental activities of daily living may be mildly impaired, but the ability to perform basic activities of daily living remains independent; the diagnostic criteria for dementia are not met.
  • MoCA-Beijing version scores were adjusted for education level: ≤13 for junior high school education or below, ≤19 for high school education, and ≤24 for university education or above; MMSE score \>24; ADL score \<23.
  • Age between 60 and 79 years.
  • Normal olfactory function assessed using the "Sniffin' Sticks" test.
  • Ability to communicate normally and complete cognitive assessments.
  • Residing in a senior care facility with no plans to leave within the next 12 weeks.

You may not qualify if:

  • Presence of other conditions known to affect cognitive function, such as psychiatric disorders (e.g., schizophrenia, depression).
  • History of asthma or any allergic conditions.
  • Use of any prescription medications that may impact cognitive function (including psychotropic drugs and others)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Interventions

Aromatherapy

Intervention Hierarchy (Ancestors)

Mind-Body TherapiesComplementary TherapiesTherapeuticsPhytotherapySensory Art TherapiesPsychotherapyBehavioral Disciplines and Activities

Study Officials

  • Yuxin Zhang, Graduate

    China Medical University, China

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Yuxin Zhang, Graduate

CONTACT

1886784523118867845231@163.com

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Student

Study Record Dates

First Submitted

July 2, 2026

First Posted

July 7, 2026

Study Start (Estimated)

September 1, 2026

Primary Completion (Estimated)

January 1, 2027

Study Completion (Estimated)

January 2, 2027

Last Updated

July 7, 2026

Record last verified: 2026-07

Data Sharing

IPD Sharing
Will not share