Evaluation Skin Stiffness Gradient on Skin After LLLT
Optimization of Low-Level Laser Therapy Via Biomechanical Properties Analysis Using Optical Coherence Tomography on Skin
1 other identifier
interventional
20
1 country
1
Brief Summary
This study evaluates the effects of Low-Level Laser Therapy (LLLT) on skin elasticity by measuring a 3x3 stiffness gradient across 9 points spaced 1 cm apart. Using an air-pressure pump integrated with an Optical Coherence Tomography (OCT) system, a deep learning model is utilized to automatically segment and track micro-scale skin movement during deformation.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Jan 2025
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 10, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 15, 2025
CompletedFirst Submitted
Initial submission to the registry
June 25, 2026
CompletedFirst Posted
Study publicly available on registry
July 2, 2026
CompletedStudy Completion
Last participant's last visit for all outcomes
August 15, 2026
ExpectedJuly 2, 2026
June 1, 2026
5 months
June 25, 2026
June 25, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Measurements skin stiffness gradient
This study evaluates the effects of Low-Level Laser Therapy (LLLT) on skin elasticity by measuring a 3x3 stiffness gradient across 9 points spaced 1 cm apart. Using an air-pressure pump integrated with an Optical Coherence Tomography (OCT) system, a deep learning model is utilized to automatically segment and track micro-scale skin movement during deformation.
Through study completion, an average of 1 year
Study Arms (4)
Three different LLLT Duration (2 min, 3 min and 5 min)
ACTIVE COMPARATORMeasuring biomechanical changes on skin after LLLT for three different duration (2 min, 3 min and 5 min) using stiffness gradient
Two different LLLT wavelength (660 and 808 nm)
ACTIVE COMPARATORMeasuring biomechanical changes on skin after LLLT for two different LLLT wavelength (660 and 808 nm) using stiffness gradient
Three different duty cycle (100%, 30% and 50%)
ACTIVE COMPARATORMeasuring biomechanical changes on skin after LLLT for three duty cycle (100%, 30% and 50%) using stiffness gradient
Two different applied frequency (1 Hz and 50 Hz)
ACTIVE COMPARATORMeasuring biomechanical changes on skin after LLLT for two different applied frequency (1 Hz and 50 Hz) using stiffness gradient
Interventions
LLLT intervention on skin biomechanical properties in three different duration and two LLLT wavelength
LLLT intervention on skin biomechanical properties in three different duty cycle and two applied frequency
Eligibility Criteria
You may qualify if:
- Healthy adult
You may not qualify if:
- People with wound and ulcers
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Asia Universitylead
Study Sites (1)
Asia University
Taichung, Wufeng, 41354, Taiwan
MeSH Terms
Conditions
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Optimization of Low-Level Laser Therapy via Biomechanical Properties Analysis Using Optical Coherence Tomography on Skin
Study Record Dates
First Submitted
June 25, 2026
First Posted
July 2, 2026
Study Start
January 10, 2025
Primary Completion
June 15, 2025
Study Completion (Estimated)
August 15, 2026
Last Updated
July 2, 2026
Record last verified: 2026-06
Data Sharing
- IPD Sharing
- Will not share