The Impact of Symptom Management Nursing Intervention on the QoL of Patients With Advanced Lung Cancer: Mediation of Self-management Efficacy and Regulation of Psychological Resilience

NCT07679165 | Completed

• 1 other identifier: 20230509
• Study Type: interventional
• Target: 176
• Locations: 1 country
• Sites: 1

Brief Summary

Symptom management nursing intervention can improve the self-management efficacy, psychological resilience, and QoL of patients with advanced lung cancer.

Conditions

Symptom Managemen; Late Stage Lung Cancer; QoL; Self Management Efficacy; Psychological Resilience; Mediating Effect

Outcome Measures

Primary Outcomes (1)

• Change in Quality of Life as measured by the Functional Assessment of Cancer Therapy-Lung (FACT-L) Scale

  The Functional Assessment of Cancer Therapy-Lung (FACT-L) scale will be used to assess changes in quality of life in patients with advanced lung cancer. The scale consists of 36 items across five domains: physical health status, social and family conditions, emotional well-being, functional capability, and lung cancer-specific supplementary concerns. Each item is scored on a 0-4 Likert scale, with total scores ranging from 0 to 144. Higher scores indicate better quality of life. The scale has demonstrated good reliability and validity in Chinese populations (Cronbach's α = 0.88-0.92).

  Baseline (within 24 hours of admission) and at 8 weeks (immediately post-intervention)

Secondary Outcomes (2)

• Change in Self-Management Efficacy as measured by the Strategies Used by People to Promote Health (SUPPH) Scale

  Baseline (within 24 hours of admission) and at 8 weeks (immediately post-intervention)

• Change in Psychological Resilience as measured by the Connor-Davidson Resilience Scale (CD-RISC)

  Baseline (within 24 hours of admission) and at 8 weeks (immediately post-intervention)

Other Outcomes (1)

• Mediating Effect of Self-Management Efficacy on the Relationship between Symptom Management Intervention and Quality of Life

  Assessed at 8 weeks (post-intervention) using post-intervention scores

Study Arms (2)

Routine nursing group

OTHER

Patients in the routine group were given routine care, including disease monitoring, medication care, diet and nutrition guidance, basic life care, routine health education on admission and discharge, symptomatic treatment of patients' discomfort symptoms, telephone follow-up twice a week to understand the patient's condition, and no systematic and personalized SM nursing intervention.

Other: routine nursing group

standardized systematic SM nursing group

OTHER

On the basis of routine nursing, implementation of systematic SM nursing intervention for 8 weeks, the specific content is as follows: (1) The intervention group was established. (2) Baseline assessment and file establishment (within 24 hours of admission).(3) Implementation of core intervention (1st to 8th week).

Other: standardized systematic SM nursing group

Interventions

routine nursing group OTHER

Patients in the routine group were given routine care, including disease monitoring, medication care, diet and nutrition guidance, basic life care, routine health education on admission and discharge, symptomatic treatment of patients' discomfort symptoms, telephone follow-up twice a week to understand the patient's condition, and no systematic and personalized SM nursing intervention.

Routine nursing group

standardized systematic SM nursing group OTHER

On the basis of routine nursing, implementation of systematic SM nursing intervention for 8 weeks, the specific content is as follows: (1) The intervention group was established. (2) Baseline assessment and file establishment (within 24 hours of admission).(3) Implementation of core intervention (1st to 8th week).

standardized systematic SM nursing group

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• According to the diagnostic criteria of primary lung cancer \[9\], the clinical stage was stage ⅢB-Ⅳ
• aged 18-75 years old
• Karnofsky performance status (KPS) ≥60 and expected survival ≥3 months
• Patients had clear consciousness and normal cognitive function, and could complete the questionnaire independently or with the assistance of the researcher
• have basic communication skills and can cooperate to complete the whole intervention
• Patients or their families informed and signed the consent form.

You may not qualify if:

• primary malignant tumors in other parts
• history of severe heart, liver, kidney and other important organ failure, severe infection or mental illness
• Unable to cooperate with the study due to cognitive impairment, visual and hearing impairment
• participating in other similar nursing intervention studies.

Sponsors & Collaborators

• Jie Zeng: lead

Study Sites (1)

Dahua Hospital, Xuhui District, Shanghai

Shanghai, Shanghai Municipality, 200031, China

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Dahua Hospital, Xuhui District, Shanghai

Study Record Dates

• First Submitted: June 25, 2026
• First Posted: July 1, 2026
• Study Start: June 10, 2023
• Primary Completion: October 27, 2024
• Study Completion: December 12, 2025
• Last Updated: July 1, 2026

Record last verified: 2026-06

Locations

CN (1)