The Relationship Between Lost Extremity Percentage and Postural Control, Neck and Low Back Pain, Daily Living Activities, and Reaction Time in Individuals With Unilateral Upper Limb Amputation

NCT07677969 | Recruiting

• 1 other identifier: FTREK25/28
• Study Type: observational
• Target: 15
• Locations: 1 country
• Sites: 1

Brief Summary

This observational study aims to examine the relationship between the percentage of limb loss and functional outcomes in individuals with unilateral upper limb amputation. Upper limb amputation can affect posture, balance control, pain levels, daily living activities, hand function, and reaction time. However, limited research has investigated how the amount of limb loss influences these outcomes. Participants between 18 and 65 years of age who use a myoelectric or bionic prosthesis will undergo a series of assessments. These assessments include measurements of postural control using a force platform, posture analysis, evaluation of neck and low back pain using a visual analog scale, daily living activities using a validated questionnaire, hand dexterity using the Box and Block Test, and reaction time using a visual stimulus device. The study does not involve any intervention or treatment. All evaluations will be performed during a single assessment session. The results of this study may help improve rehabilitation planning and provide better understanding of functional changes associated with different levels of limb loss in people with upper limb amputation.

Conditions

Upper Limb Amputation; Postural Control; Neck Pain; Low Back Pain; Daily Activities; Reaction Time

Keywords

Upper Limb Amputation; Postural Control; Neck Pain; low back pain; Daily Living Activities; reaction time

Outcome Measures

Primary Outcomes (1)

• Daily living activity score

  In upper extremity amputees, daily living activities and occupational skills will be assessed using a questionnaire. (0-100 score, Survey on Activities of Daily Living and Occupations of Upper Extremity Amputees)

  through study completion, an average of 1 year

Secondary Outcomes (5)

• Postural Sway and Limits of Stability

  through study completion, an average of 1 year

• Postural Sway and Limits of Stability

  through study completion, an average of 1 year

• Neck and Back Pain Intensity

  through study completion, an average of 1 year

• Hand Dexterity

  through study completion, an average of 1 year

• Reaction Time

  through study completion, an average of 1 year

Study Arms (1)

Unilateral Upper Limb Amputation Group

Participants in this cohort are adults aged 18 to 65 years with unilateral upper limb amputation who use a myoelectric or bionic prosthesis. Individuals must have been using their current prosthesis for at least three months and have a minimum of one year of prosthesis experience. Participants with additional neurological or orthopedic conditions, bilateral amputation, or passive/cosmetic prosthesis use are excluded. This is an observational study. No interventional procedures are performed. All participants undergo a single assessment session including measurements of postural control, posture, neck and low back pain, daily living activities, hand dexterity, and reaction time.

Other: This is an observational study. No interventional procedures are performed. All assessments are non-invasive measurements.

Interventions

This is an observational study. No interventional procedures are performed. All assessments are non-invasive measurements. OTHER

This is an observational study. No interventional procedures are performed. All assessments are non-invasive measurements.

Unilateral Upper Limb Amputation Group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

This study population consists of adults aged 18-65 years with unilateral upper limb amputation who use a myoelectric or bionic prosthesis. Participants are recruited from clinical and rehabilitation settings and meet predefined inclusion and exclusion criteria. All individuals undergo a single-session assessment to evaluate postural control, pain, daily living activities, hand function, and reaction time.

You may qualify if:

• Adults aged 18-65 years
• Unilateral upper limb amputation
• Use of a myoelectric or bionic prosthesis for at least 1 year
• Current prosthesis use for a minimum of 3 months

You may not qualify if:

• Bilateral upper limb amputation
• Additional amputation of another limb
• Use of passive or cosmetic prosthesis
• Presence of neurological or other significant orthopedic disorders unrelated to amputation

Sponsors & Collaborators

• Hacettepe University: lead

Study Sites (1)

Hacettepe university

Ankara, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Neck Pain; Low Back Pain

Condition Hierarchy (Ancestors)

Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Back Pain

Central Study Contacts

ASLI BEBEK, MSc

CONTACT

+905364037230; aslisabanci97@gmail.com

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: February 14, 2026
• First Posted: July 1, 2026
• Study Start: January 1, 2026
• Primary Completion: August 1, 2026
• Study Completion (Estimated): December 1, 2026
• Last Updated: July 1, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)